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About

Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with autoimmune diseases. Its lead product candidate is resecabtagene autoleucel, a 4-1BB co-stimulatory domain-containing fully human CD19-CAR T, which is in Phase 1/2 clinical trials for the treatment of dermatomyositis, anti-synthetase syndrome, immune-mediated necrotizing myopathy, juvenile myositis, lupus nephritis, non-renal systemic lupus erythematosus, relapsing and progressive multiple sclerosis, mucocutaneous and mucosal pemphigus vulgaris (PV), systemic sclerosis, and generalized myasthenia gravis. The company also develops DSG3-CAART, a CAAR T cell therapy that is in Phase 1 clinical trial for the treatment of mucosal PV; and MuSK-CAART, an investigational cell therapy in Phase 1 trial for treating patients with anti-muscle-specific kinase (MuSK) antibody positive myasthenia gravis. It has collaborations with the University of Pennsylvania and the Children's Hospital of Philadelphia; Nanjing IASO Biotherapeutics Co., Ltd; Oxford Biomedica; Autolus Holdings (UK) Limited; and WuXi Advanced Therapies, Inc. The company was formerly known as Tycho Therapeutics, Inc. and changed its name to Cabaletta Bio, Inc. in August 2018. Cabaletta Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.

Fundamentals
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Sector Healthcare Industry Biotechnology Market Cap 330.19M
Enterprise Value 182.56M Income -158.52M Sales —
Book/sh 1.45 Cash/sh 1.66 Dividend Yield —
Payout 0.00% Employees 148 IPO —
P/E — Forward P/E -2.05 PEG —
P/S — P/B 2.37 P/C —
EV/EBITDA -1.13 EV/Sales — Quick Ratio 3.50
Current Ratio 3.60 Debt/Eq 18.48 LT Debt/Eq —
EPS (ttm) -2.40 EPS next Y -1.68 EPS Growth —
Revenue Growth — Earnings 2026-03-30 ROA -51.82%
ROE -101.06% ROIC — Gross Margin 0.00%
Oper. Margin 0.00% Profit Margin 0.00% Shs Outstand 96.27M
Shs Float 70.98M Short Float 19.73% Short Ratio 4.77
Short Interest — 52W High 3.67 52W Low 0.99
Beta 3.30 Avg Volume 2.91M Volume 263.65K
Target Price $13.12 Recom Strong_buy Prev Close $3.29
Price $3.43 Change 4.26%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$13.13
Mean price target
2. Current target
$3.74
Latest analyst target
3. DCF / Fair value
$-13.76
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$3.74
Low
$2.00
High
$30.00
Mean
$13.13

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2025-10-31 main Cantor Fitzgerald Overweight → Overweight $30
2025-10-10 reit HC Wainwright & Co. Buy → Buy $16
2025-09-05 reit Cantor Fitzgerald Overweight → Overweight $15
2025-08-14 main Citigroup Buy → Buy $10
2025-08-08 main Wells Fargo Equal-Weight → Equal-Weight $2
2025-08-08 main Guggenheim Buy → Buy $15
2025-06-11 reit HC Wainwright & Co. Buy → Buy $25
2025-05-16 main Citigroup Buy → Buy $13
2025-05-16 main Guggenheim Buy → Buy $25
2025-05-15 main Guggenheim Buy → Buy $25
2025-04-01 main Wells Fargo Equal-Weight → Equal-Weight $3
2025-04-01 reit Guggenheim Buy → Buy $23
2025-04-01 main UBS Buy → Buy $7
2025-04-01 main Morgan Stanley Overweight → Overweight $22
2025-04-01 reit HC Wainwright & Co. Buy → Buy $25
2025-02-18 reit HC Wainwright & Co. Buy → Buy $25
2025-01-17 reit HC Wainwright & Co. Buy → Buy $25
2024-12-20 down Evercore ISI Group Outperform → In-Line $6
2024-12-19 down Wells Fargo Overweight → Equal-Weight $6
2024-11-18 reit HC Wainwright & Co. Buy → Buy $25
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 11061 25261 — Purchase at price 2.28 per share. SIMON MARK Director — 2026-01-21 00:00:00 D
1 45000 100778 — Purchase at price 2.24 per share. NICHTBERGER STEVEN Chief Executive Officer — 2026-01-21 00:00:00 D
2 22725 50322 — Purchase at price 2.21 per share. TOMASELLO SHAWN CLINE Director — 2026-01-21 00:00:00 I
3 8800 19888 — Purchase at price 2.26 per share. CHANG DAVID J. M.D. Officer — 2026-01-21 00:00:00 D
4 4405 9982 — Purchase at price 2.27 per share. BOLLARD CATHERINE M.D. Director — 2026-01-21 00:00:00 D
5 11312 24763 — Purchase at price 2.19 per share. BINDER GWENDOLYN Officer — 2026-01-21 00:00:00 D
6 6600 14979 — Purchase at price 2.27 per share. GERARD MICHAEL General Counsel — 2026-01-21 00:00:00 D
7 22170 50215 — Purchase at price 2.26 per share. GAVEL STEVE Officer — 2026-01-21 00:00:00 D
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems0.000.000.000.00
TaxRateForCalcs0.000.000.000.00
NormalizedEBITDA-113.41M-66.25M-52.96M-45.58M
NetIncomeFromContinuingOperationNetMinorityInterest-115.86M-67.67M-52.98M-46.29M
ReconciledDepreciation1.71M1.43M1.18M733.00K
EBITDA-113.41M-66.25M-52.96M-45.58M
EBIT-115.12M-67.67M-54.14M-46.31M
NetInterestIncome9.28M6.99M1.16M24.00K
InterestExpense748.00K0.00
InterestIncome10.03M6.99M1.16M24.00K
NormalizedIncome-115.86M-67.67M-52.98M-46.29M
NetIncomeFromContinuingAndDiscontinuedOperation-115.86M-67.67M-52.98M-46.29M
TotalExpenses125.14M74.66M54.14M46.31M
TotalOperatingIncomeAsReported-125.14M-74.66M-54.14M-46.31M
DilutedAverageShares49.51M40.95M29.27M25.72M
BasicAverageShares49.51M39.19M29.27M25.72M
DilutedEPS-2.34-1.65-1.81-1.80
BasicEPS-2.34-1.65-1.81-1.80
DilutedNIAvailtoComStockholders-115.86M-67.67M-52.98M-46.29M
NetIncomeCommonStockholders-115.86M-67.67M-52.98M-46.29M
NetIncome-115.86M-67.67M-52.98M-46.29M
NetIncomeIncludingNoncontrollingInterests-115.86M-67.67M-52.98M-46.29M
NetIncomeContinuousOperations-115.86M-67.67M-52.98M-46.29M
PretaxIncome-115.86M-67.67M-52.98M-46.29M
NetNonOperatingInterestIncomeExpense9.28M6.99M1.16M24.00K
InterestExpenseNonOperating748.00K0.00
InterestIncomeNonOperating10.03M6.99M1.16M24.00K
OperatingIncome-125.14M-74.66M-54.14M-46.31M
OperatingExpense125.14M74.66M54.14M46.31M
ResearchAndDevelopment97.20M55.42M39.30M32.49M
SellingGeneralAndAdministration27.94M19.24M14.84M13.82M
GeneralAndAdministrativeExpense27.94M19.24M14.84M13.82M
OtherGandA27.94M19.24M14.84M13.82M
TotalRevenue0.000.000.000.00
OperatingRevenue0.000.000.000.00
Line Item2024-12-312023-12-312022-12-312021-12-31
OrdinarySharesNumber50.74M46.38M29.45M28.93M
ShareIssued50.74M46.38M29.45M28.93M
TotalDebt15.60M5.02M5.14M0.00
TangibleBookValue152.34M236.20M104.52M117.96M
InvestedCapital152.34M236.20M104.52M117.96M
WorkingCapital139.59M228.50M99.34M116.16M
NetTangibleAssets152.34M236.20M104.52M117.96M
CapitalLeaseObligations15.60M5.02M5.14M0.00
CommonStockEquity152.34M236.20M104.52M117.96M
TotalCapitalization152.34M236.20M104.52M117.96M
TotalEquityGrossMinorityInterest152.34M236.20M104.52M117.96M
StockholdersEquity152.34M236.20M104.52M117.96M
GainsLossesNotAffectingRetainedEarnings0.0039.00K-47.00K0.00
OtherEquityAdjustments39.00K-47.00K
RetainedEarnings-349.10M-233.24M-165.56M-112.59M
AdditionalPaidInCapital501.44M469.40M270.13M230.54M
CapitalStock1.00K0.000.000.00
CommonStock1.00K0.000.000.00
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest32.71M17.45M12.45M8.38M
TotalNonCurrentLiabilitiesNetMinorityInterest5.62M1.46M2.96M0.00
LongTermDebtAndCapitalLeaseObligation5.62M1.46M2.96M0.00
LongTermCapitalLeaseObligation5.62M1.46M2.96M0.00
CurrentLiabilities27.09M15.99M9.49M8.38M
OtherCurrentLiabilities40.00K40.00K39.00K54.00K
CurrentDebtAndCapitalLeaseObligation9.97M3.56M2.18M
CurrentCapitalLeaseObligation9.97M3.56M2.18M0.00
PensionandOtherPostRetirementBenefitPlansCurrent8.31M5.20M3.52M2.98M
PayablesAndAccruedExpenses8.76M7.19M3.76M5.35M
CurrentAccruedExpenses3.83M2.65M1.29M3.02M
Payables4.92M4.55M2.46M2.33M
AccountsPayable4.92M4.55M2.46M2.33M
TotalAssets185.05M253.65M116.97M126.34M
TotalNonCurrentAssets18.37M9.16M8.13M1.79M
OtherNonCurrentAssets2.29M1.71M565.00K357.00K
NetPPE16.08M7.45M7.57M1.44M
AccumulatedDepreciation-5.51M-3.79M-2.37M-1.19M
GrossPPE21.58M11.25M9.94M2.63M
Leases113.00K113.00K113.00K57.00K
OtherProperties21.00M10.80M9.49M2.24M
MachineryFurnitureEquipment473.00K330.00K330.00K330.00K
Properties0.000.000.000.00
CurrentAssets166.68M244.49M108.83M124.54M
OtherCurrentAssets2.71M3.24M2.29M2.32M
PrepaidAssets2.32M
CashCashEquivalentsAndShortTermInvestments163.96M241.25M106.55M122.22M
OtherShortTermInvestments0.0048.01M24.94M0.00
CashAndCashEquivalents163.96M193.24M81.61M122.22M
CashEquivalents192.50M81.61M
CashFinancial743.00K
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-90.43M-54.24M-48.83M-35.27M
RepaymentOfDebt-897.00K0.00
IssuanceOfCapitalStock10.88M185.20M32.85M48.25M
CapitalExpenditure-2.21M-687.00K-2.45M-1.17M
InterestPaidSupplementalData748.00K0.00
EndCashPosition163.96M193.24M81.61M122.22M
BeginningCashPosition193.24M81.61M122.22M101.43M
EffectOfExchangeRateChanges-20.00K0.00
ChangesInCash-29.26M111.63M-40.62M20.79M
FinancingCashFlow11.68M187.63M32.98M48.90M
CashFlowFromContinuingFinancingActivities11.68M187.63M32.98M48.90M
ProceedsFromStockOptionExercised1.70M2.43M127.00K650.00K
NetCommonStockIssuance10.88M185.20M32.85M48.25M
CommonStockIssuance10.88M185.20M32.85M48.25M
NetIssuancePaymentsOfDebt-897.00K0.00
NetLongTermDebtIssuance-897.00K0.00
LongTermDebtPayments-897.00K0.00
InvestingCashFlow47.29M-22.45M-27.22M6.00M
CashFlowFromContinuingInvestingActivities47.29M-22.45M-27.22M6.00M
NetInvestmentPurchaseAndSale49.50M-21.76M-24.76M7.17M
SaleOfInvestment49.50M62.50M25.00M7.17M
PurchaseOfInvestment0.00-84.26M-49.76M0.00
NetPPEPurchaseAndSale-2.21M-687.00K-2.45M-1.17M
PurchaseOfPPE-2.21M-687.00K-2.45M-1.17M
OperatingCashFlow-88.22M-53.55M-46.38M-34.11M
CashFlowFromContinuingOperatingActivities-88.22M-53.55M-46.38M-34.11M
ChangeInWorkingCapital1.61M101.00K-4.30M5.58M
ChangeInOtherCurrentLiabilities-3.29M-2.46M-2.91M0.00
ChangeInOtherCurrentAssets-584.00K-1.14M-208.00K-58.00K
ChangeInPayablesAndAccruedExpense4.96M4.66M-1.21M3.08M
ChangeInAccruedExpense3.95M2.98M-1.19M2.11M
ChangeInPayable1.01M1.68M-28.00K975.00K
ChangeInAccountPayable1.01M1.68M-28.00K975.00K
ChangeInPrepaidAssets528.00K-954.00K32.00K2.55M
OtherNonCashItems6.34M2.48M3.04M
StockBasedCompensation19.46M11.34M6.90M5.80M
AmortizationOfSecurities-1.53M-1.22M-223.00K62.00K
DepreciationAmortizationDepletion1.71M1.43M1.18M733.00K
DepreciationAndAmortization1.71M1.43M1.18M733.00K
Depreciation1.71M1.43M1.18M733.00K
OperatingGainsLosses38.00K
NetForeignCurrencyExchangeGainLoss38.00K0.00
NetIncomeFromContinuingOperations-115.86M-67.67M-52.98M-46.29M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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