Symbols / LXRX $1.84 -1.60% Lexicon Pharmaceuticals, Inc.

Healthcare • Biotechnology • United States • NCM
LXRX Chart
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About

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company develops sotagliflozin, an orally-delivered small molecule drug for the treatment of hypertrophic cardiomyopathy, and ZYNQUISTA (sotagliflozin) for the treatment of type 1 diabetes. It also commercializes INPEFA (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, CKD, and other cardiovascular risk factors. In addition, the company develops LX9851, an orally-delivered small molecule drug candidate for the treatment of obesity and associated cardiometabolic disorders, and pilavapadin (LX9211), an orally-delivered small molecule drug candidate for the treatment of neuropathic pain. It has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.

Fundamentals
Scroll to Statements
Market Cap 779.57M Enterprise Value 745.58M Income -50.34M Sales 49.80M Book/sh 0.30 Cash/sh 0.23
Dividend Yield — Payout 0.00% Employees 81 IPO — P/E — Forward P/E -8.84
PEG -13.77 P/S 15.65 P/B 6.22 P/C — EV/EBITDA -15.44 EV/Sales 14.97
Quick Ratio 4.73 Current Ratio 4.88 Debt/Eq 57.87 LT Debt/Eq — EPS (ttm) -0.14 EPS next Y -0.21
EPS Growth — Revenue Growth -79.30% Earnings 2026-05-12 ROA -12.65% ROE -39.72% ROIC —
Gross Margin 86.82% Oper. Margin -269.07% Profit Margin -101.08% Shs Outstand 423.68M Shs Float 417.80M Short Float 10.67%
Short Ratio 8.56 Short Interest — 52W High 1.95 52W Low 0.51 Beta 0.95 Avg Volume 2.88M
Volume 1.65M Target Price $3.36 Recom Buy Prev Close $1.87 Price $1.84 Change -1.60%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$3.36
Mean price target
2. Current target
$1.84
Latest analyst target
3. DCF / Fair value
$-2.03
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$1.84
Low
$1.00
High
$6.00
Mean
$3.36

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-23 reit HC Wainwright & Co. Buy → Buy $6
2026-03-10 main Citigroup Buy → Buy $2
2026-03-05 main HC Wainwright & Co. Buy → Buy $6
2025-09-02 reit HC Wainwright & Co. Buy → Buy $4
2025-08-07 main Citigroup Buy → Buy $2
2025-06-24 reit HC Wainwright & Co. Buy → Buy $4
2025-03-28 reit HC Wainwright & Co. Buy → Buy $4
2025-03-07 main Piper Sandler Overweight → Overweight $6
2025-03-07 reit Needham Hold → Hold —
2025-03-07 reit HC Wainwright & Co. Buy → Buy $4
2025-03-04 down Leerink Partners Outperform → Market Perform $1
2025-03-03 reit HC Wainwright & Co. Buy → Buy $4
2025-03-03 reit Needham Hold → Hold —
2025-01-29 reit HC Wainwright & Co. Buy → Buy $4
2025-01-29 reit Needham Hold → Hold —
2024-12-23 reit Needham Hold → Hold —
2024-11-25 reit Needham — → Hold —
2024-11-22 reit Needham — → Hold —
2024-11-13 reit HC Wainwright & Co. Buy → Buy $6
2024-11-13 reit Needham — → Hold —
News
RSS: Latest LXRX news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-02-27 COIANTE SCOTT M Chief Financial Officer — 160,237 — —
2026-02-27 CRUM BRIAN T General Counsel — 273,006 — —
2026-02-27 DEFRANCESCO LISA Officer — 152,864 — —
2026-02-27 GRANOWITZ CRAIG B. M.D., PH.D. Officer — 312,276 — —
2026-02-27 MCDERMOTT WENDY Officer — 224,406 — —
2026-02-27 EXTON MICHAEL Chief Executive Officer — 503,263 — —
2026-02-27 MARTENS RACHEL YAP Officer — 67,090 — —
2026-02-27 GOPINATHAN SUMA Officer — 99,950 — —
2026-02-25 DEBBANE RAYMOND Director — 2,000 $1.49 $2,980
2026-02-23 DEBBANE RAYMOND Director — 100,000 $1.47 $147,000
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
49.80
+60.24%
31.08
+2481.48%
1.20
+766.19%
0.14
Operating Revenue
49.80
+60.24%
31.08
+2481.48%
1.20
+766.19%
0.14
Cost Of Revenue
0.27
-55.52%
0.62
+624.71%
0.09
0.00
Reconciled Cost Of Revenue
0.27
-55.52%
0.62
+624.71%
0.09
0.00
Gross Profit
49.53
+62.58%
30.46
+2622.52%
1.12
+705.04%
0.14
Operating Expense
98.44
-56.75%
227.58
+31.65%
172.87
+71.33%
100.90
Research And Development
61.12
-27.65%
84.48
+43.46%
58.89
+11.49%
52.82
Selling General And Administration
37.32
-73.92%
143.10
+25.55%
113.98
+137.05%
48.08
Total Expenses
98.71
-56.74%
228.20
+31.94%
172.95
+71.41%
100.90
Operating Income
-48.91
+75.19%
-197.12
-14.77%
-171.75
-70.45%
-100.76
Total Operating Income As Reported
-48.91
+75.19%
-197.12
-14.77%
-171.75
-70.45%
-100.76
EBITDA
-41.38
+77.55%
-184.29
-12.74%
-163.46
-65.55%
-98.74
Normalized EBITDA
-41.38
+77.55%
-184.29
-12.74%
-163.46
-65.55%
-98.74
Reconciled Depreciation
0.62
+16.29%
0.53
-3.61%
0.55
+29.74%
0.43
EBIT
-42.00
+77.27%
-184.82
-12.69%
-164.02
-65.40%
-99.16
Total Unusual Items
—
—
—
0.00
Total Unusual Items Excluding Goodwill
—
—
—
0.00
Special Income Charges
—
—
—
0.00
Impairment Of Capital Assets
—
—
—
0.00
Net Income
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Pretax Income
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Non Operating Interest Income Expense
-1.43
+56.48%
-3.29
+38.80%
-5.37
-353.46%
-1.18
Interest Expense Non Operating
8.34
-46.47%
15.58
+18.91%
13.10
+371.26%
2.78
Net Interest Income
-1.43
+56.48%
-3.29
+38.80%
-5.37
-353.46%
-1.18
Interest Expense
8.34
-46.47%
15.58
+18.91%
13.10
+371.26%
2.78
Interest Income Non Operating
6.91
-43.80%
12.29
+58.99%
7.73
+384.46%
1.60
Interest Income
6.91
-43.80%
12.29
+58.99%
7.73
+384.46%
1.60
Gain On Sale Of Business
—
—
—
0.00
Tax Provision
—
—
—
—
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Income From Continuing Operation Net Minority Interest
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Income From Continuing And Discontinued Operation
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Income Continuous Operations
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Normalized Income
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Net Income Common Stockholders
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Diluted EPS
—
-0.63
+20.25%
-0.79
-27.42%
-0.62
Basic EPS
—
-0.63
+20.25%
-0.79
-27.42%
-0.62
Basic Average Shares
—
320.03
+44.73%
221.13
+33.43%
165.73
Diluted Average Shares
—
320.03
+44.73%
221.13
+33.43%
165.73
Diluted NI Availto Com Stockholders
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
184.99
-38.01%
298.42
+30.07%
229.43
+18.08%
194.30
Current Assets
101.89
-58.61%
246.19
+39.45%
176.55
+25.33%
140.87
Cash Cash Equivalents And Short Term Investments
96.23
-59.56%
237.96
+39.95%
170.03
+22.89%
138.36
Cash And Cash Equivalents
34.33
-48.50%
66.66
+196.71%
22.46
-51.53%
46.34
Other Short Term Investments
61.90
-63.86%
171.30
+16.09%
147.56
+60.37%
92.01
Receivables
2.38
-31.36%
3.47
+243.86%
1.01
+3507.14%
0.03
Accounts Receivable
2.38
-31.36%
3.47
+243.86%
1.01
+3507.14%
0.03
Inventory
0.28
+21.65%
0.23
-39.37%
0.38
0.00
Raw Materials
—
0.10
0.00
0.00
Work In Process
—
0.00
-100.00%
0.10
0.00
Finished Goods
—
0.13
-54.45%
0.28
0.00
Prepaid Assets
—
—
—
—
Other Current Assets
3.00
-33.80%
4.53
-11.66%
5.13
+106.77%
2.48
Total Non Current Assets
83.09
+59.10%
52.23
-1.24%
52.88
-1.03%
53.43
Net PPE
9.18
+25.49%
7.32
-2.60%
7.51
-11.41%
8.48
Gross PPE
11.89
+26.44%
9.40
-21.97%
12.05
-3.31%
12.46
Accumulated Depreciation
-2.71
-29.77%
-2.09
+54.03%
-4.54
-13.91%
-3.98
Properties
0.00
0.00
0.00
0.00
Buildings And Improvements
7.32
+51.45%
4.83
-12.53%
5.52
-13.78%
6.41
Machinery Furniture Equipment
2.39
+0.00%
2.39
-44.97%
4.35
+8.59%
4.00
Other Properties
—
—
—
6.82
Leases
2.18
+0.00%
2.18
+0.00%
2.18
+6.14%
2.05
Goodwill And Other Intangible Assets
44.54
+0.00%
44.54
+0.00%
44.54
+0.00%
44.54
Goodwill
44.54
+0.00%
44.54
+0.00%
44.54
+0.00%
44.54
Other Non Current Assets
29.37
+7880.43%
0.37
-55.56%
0.83
+100.97%
0.41
Total Liabilities Net Minority Interest
77.45
-49.20%
152.47
+11.85%
136.32
+76.64%
77.17
Current Liabilities
20.87
-53.88%
45.25
+43.43%
31.55
+36.14%
23.17
Payables And Accrued Expenses
8.21
-72.02%
29.36
+42.09%
20.66
+47.06%
14.05
Payables
3.08
-79.17%
14.80
+2.86%
14.39
+38.42%
10.39
Accounts Payable
3.08
-79.17%
14.80
+2.86%
14.39
+38.42%
10.39
Current Accrued Expenses
5.13
-64.75%
14.56
+132.03%
6.28
+71.64%
3.66
Pensionand Other Post Retirement Benefit Plans Current
6.42
-56.40%
14.71
+53.39%
9.59
+22.49%
7.83
Current Debt And Capital Lease Obligation
6.24
+430.81%
1.18
-8.99%
1.29
+0.00%
1.29
Current Debt
4.59
—
—
—
Other Current Borrowings
4.59
—
—
—
Current Capital Lease Obligation
1.64
+39.74%
1.18
-8.99%
1.29
+0.00%
1.29
Total Non Current Liabilities Net Minority Interest
56.58
-47.23%
107.22
+2.34%
104.77
+94.01%
54.00
Long Term Debt And Capital Lease Obligation
56.58
-47.23%
107.22
+2.34%
104.77
+94.01%
54.00
Long Term Debt
49.41
-50.74%
100.30
+0.79%
99.51
+104.84%
48.58
Long Term Capital Lease Obligation
7.17
+3.61%
6.92
+31.51%
5.26
-2.93%
5.42
Stockholders Equity
107.54
-26.32%
145.95
+56.75%
93.11
-20.50%
117.12
Common Stock Equity
107.54
-26.32%
145.95
+56.75%
93.11
-20.50%
117.12
Capital Stock
0.37
+0.83%
0.36
+48.16%
0.24
+29.63%
0.19
Common Stock
0.37
+0.83%
0.36
+48.16%
0.24
+29.63%
0.19
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
365.85
+0.78%
363.02
+47.69%
245.79
+29.90%
189.21
Ordinary Shares Number
363.47
+0.55%
361.49
+47.59%
244.92
+29.78%
188.73
Treasury Shares Number
2.38
+55.89%
1.53
+76.04%
0.87
+77.86%
0.49
Additional Paid In Capital
2,129.91
+0.59%
2,117.32
+13.68%
1,862.56
+8.98%
1,709.14
Retained Earnings
-2,017.58
-2.56%
-1,967.24
-11.34%
-1,766.84
-11.14%
-1,589.72
Gains Losses Not Affecting Retained Earnings
0.03
-74.79%
0.12
+283.87%
0.03
+107.24%
-0.43
Treasury Stock
5.19
+12.39%
4.62
+59.97%
2.88
+39.98%
2.06
Other Equity Adjustments
0.03
-74.79%
0.12
+283.87%
0.03
+107.24%
-0.43
Total Equity Gross Minority Interest
107.54
-26.32%
145.95
+56.75%
93.11
-20.50%
117.12
Total Capitalization
156.95
-36.27%
246.25
+27.84%
192.62
+16.24%
165.70
Working Capital
81.03
-59.68%
200.94
+38.58%
145.00
+23.20%
117.69
Invested Capital
161.54
-34.40%
246.25
+27.84%
192.62
+16.24%
165.70
Total Debt
62.82
-42.05%
108.40
+2.20%
106.06
+91.82%
55.29
Net Debt
19.68
-41.51%
33.64
-56.33%
77.04
+3348.66%
2.23
Capital Lease Obligations
8.82
+8.85%
8.10
+23.54%
6.56
-2.37%
6.71
Net Tangible Assets
62.99
-37.88%
101.41
+108.80%
48.57
-33.09%
72.58
Tangible Book Value
62.99
-37.88%
101.41
+108.80%
48.57
-33.09%
72.58
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-67.85
+62.05%
-178.78
-10.43%
-161.90
-82.21%
-88.85
Cash Flow From Continuing Operating Activities
-67.85
+62.05%
-178.78
-10.43%
-161.90
-82.21%
-88.85
Net Income From Continuing Operations
-50.34
+74.88%
-200.40
-13.15%
-177.12
-73.74%
-101.94
Depreciation And Amortization
0.62
+16.29%
0.53
-3.61%
0.55
+29.74%
0.43
Other Non Cash Items
-0.04
-101.58%
2.66
-19.14%
3.29
+343.45%
0.74
Stock Based Compensation
12.52
-7.27%
13.50
-5.86%
14.34
+24.48%
11.52
Asset Impairment Charge
—
—
—
0.00
Deferred Tax
—
—
—
—
Deferred Income Tax
—
—
—
—
Operating Gains Losses
—
—
—
0.00
Gain Loss On Sale Of PPE
—
0.00
0.00
-100.00%
0.00
Change In Working Capital
-26.89
-288.89%
14.24
+435.46%
2.66
+561.44%
0.40
Change In Receivables
1.09
+144.21%
-2.46
-150.81%
-0.98
-6914.29%
-0.01
Changes In Account Receivables
1.09
+144.21%
-2.46
-150.81%
-0.98
-6914.29%
-0.01
Change In Inventory
-0.05
-133.33%
0.15
+139.37%
-0.38
0.00
Change In Prepaid Assets
1.53
+156.19%
0.60
+120.63%
-2.90
-817.41%
-0.32
Change In Payables And Accrued Expense
-30.22
-304.19%
14.80
+129.33%
6.45
+8392.11%
0.08
Change In Payable
-30.22
-304.19%
14.80
+129.33%
6.45
+8392.11%
0.08
Change In Account Payable
-30.22
-304.19%
14.80
+129.33%
6.45
+8392.11%
0.08
Change In Other Current Assets
0.76
-34.29%
1.15
+146.68%
0.47
-28.81%
0.66
Investing Cash Flow
113.02
+834.95%
-15.38
+69.21%
-49.94
+29.73%
-71.08
Cash Flow From Continuing Investing Activities
113.02
+834.95%
-15.38
+69.21%
-49.94
+29.73%
-71.08
Net PPE Purchase And Sale
0.00
+100.00%
-1.03
-119.36%
-0.47
+64.56%
-1.33
Purchase Of PPE
0.00
+100.00%
-1.03
-119.36%
-0.47
+64.56%
-1.33
Sale Of PPE
—
—
—
0.00
Capital Expenditure
—
-1.03
-119.36%
-0.47
+64.56%
-1.33
Net Investment Purchase And Sale
113.02
+887.76%
-14.35
+71.00%
-49.47
+29.07%
-69.75
Purchase Of Investment
-139.84
+57.46%
-328.75
-47.19%
-223.34
-66.74%
-133.95
Sale Of Investment
252.86
-19.57%
314.40
+80.82%
173.87
+170.84%
64.20
Net Business Purchase And Sale
—
—
—
0.00
Gain Loss On Sale Of Business
—
—
—
0.00
Financing Cash Flow
-48.50
-120.35%
238.35
+26.81%
187.96
+32.17%
142.21
Cash Flow From Continuing Financing Activities
-48.50
-120.35%
238.35
+26.81%
187.96
+32.17%
142.21
Net Issuance Payments Of Debt
-48.00
0.00
-100.00%
49.96
+2.24%
48.87
Issuance Of Debt
0.00
0.00
-100.00%
49.96
+2.24%
48.87
Repayment Of Debt
-48.00
0.00
0.00
—
Long Term Debt Issuance
0.00
0.00
-100.00%
49.96
+2.24%
48.87
Long Term Debt Payments
-48.00
0.00
0.00
—
Net Long Term Debt Issuance
-48.00
0.00
-100.00%
49.96
+2.24%
48.87
Net Common Stock Issuance
-0.57
+66.94%
-1.73
-101.25%
138.00
+47.84%
93.34
Common Stock Payments
-0.57
+66.94%
-1.73
-109.95%
-0.82
+4.63%
-0.86
Repurchase Of Capital Stock
-0.57
+66.94%
-1.73
-109.95%
-0.82
+4.63%
-0.86
Proceeds From Stock Option Exercised
0.07
+14.06%
0.06
0.00
0.00
Net Other Financing Charges
—
-1.31
—
—
Changes In Cash
-3.33
-107.54%
44.19
+285.05%
-23.88
-34.76%
-17.72
Beginning Cash Position
66.66
+196.71%
22.46
-51.53%
46.34
-27.66%
64.06
End Cash Position
63.33
-5.00%
66.66
+196.71%
22.46
-51.53%
46.34
Free Cash Flow
-67.85
+62.27%
-179.81
-10.74%
-162.37
-80.05%
-90.18
Interest Paid Supplemental Data
8.33
-35.52%
12.92
+28.46%
10.06
+339.36%
2.29
Amortization Of Securities
-3.71
+60.11%
-9.30
-65.66%
-5.62
0.00
Common Stock Issuance
0.00
0.00
-100.00%
138.82
+47.36%
94.20
Issuance Of Capital Stock
0.00
-100.00%
241.32
+73.83%
138.82
+47.36%
94.20
Net Preferred Stock Issuance
0.00
-100.00%
241.32
0.00
0.00
Preferred Stock Issuance
0.00
-100.00%
241.32
0.00
0.00
Sale Of Business
—
—
—
0.00
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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