Symbols / MDGL Stock $529.14 +0.27% Madrigal Pharmaceuticals, Inc.

Healthcare • Biotechnology • United States • NMS
MDGL (Stock) Chart
O: — H: — L: — C: — V: —
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About

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.

Stock Fundamentals
Scroll to Statements
Market Cap 12.14B Enterprise Value 11.50B Income -288.28M Sales 958.40M Book/sh 26.39 Cash/sh 42.88
Dividend Yield — Payout 0.00% Employees 915 IPO — P/E — Forward P/E 41.36
PEG — P/S 12.67 P/B 20.05 P/C — EV/EBITDA -38.52 EV/Sales 12.00
Quick Ratio 3.60 Current Ratio 4.01 Debt/Eq 57.68 LT Debt/Eq — EPS (ttm) -12.86 EPS next Y 12.79
EPS Growth — Revenue Growth 210.80% Earnings 2026-05-06 ROA -16.30% ROE -42.49% ROIC —
Gross Margin 94.14% Oper. Margin -18.57% Profit Margin -30.08% Shs Outstand 22.94M Shs Float 12.49M Short Float 19.65%
Short Ratio 10.69 Short Interest — 52W High 615.00 52W Low 265.00 Beta -1.01 Avg Volume 361.06K
Volume 197.80K Target Price $672.79 Recom Strong_buy Prev Close $527.69 Price $529.14 Change 0.27%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$672.79
Mean price target
2. Current target
$529.14
Latest analyst target
3. DCF / Fair value
$-90.30
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$529.14
Low
$529.00
High
$964.00
Mean
$672.79

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-02-20 main B of A Securities Neutral → Neutral $529
2026-01-28 init Barclays — → Overweight $964
2026-01-20 main Citizens Market Outperform → Market Outperform $745
2025-12-19 main Piper Sandler Overweight → Overweight $900
2025-12-11 main B. Riley Securities Buy → Buy $670
2025-11-21 main HC Wainwright & Co. Buy → Buy $620
2025-11-20 main Oppenheimer Outperform → Outperform $650
2025-11-19 main Truist Securities Buy → Buy $640
2025-11-13 main Canaccord Genuity Buy → Buy $587
2025-11-11 main HC Wainwright & Co. Buy → Buy $568
2025-11-05 up Cantor Fitzgerald Neutral → Overweight —
2025-11-05 main Citizens Market Outperform → Market Outperform $527
2025-11-03 up B of A Securities Underperform → Neutral $445
2025-10-15 main Piper Sandler Overweight → Overweight $540
2025-10-15 init Truist Securities — → Buy $580
2025-10-10 main Oppenheimer Outperform → Outperform $590
2025-09-29 main B. Riley Securities Buy → Buy $560
2025-09-12 main Canaccord Genuity Buy → Buy $526
2025-08-26 main TD Cowen Buy → Buy $554
2025-08-20 main JMP Securities Market Outperform → Market Outperform $485
News
RSS: Latest MDGL news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-03-06 SIBOLD WILLIAM JOHN Chief Executive Officer — 1,663 $431.94 $718,316
2026-03-06 DIER MARDI C Chief Financial Officer — 1,982 $425.08 $853,993
2026-03-06 HUNTSMAN CAROLE A Officer — 419 $431.94 $180,983
2026-03-06 KELLEY SHANNON T General Counsel — 360 $431.94 $155,498
2026-03-06 TAUB REBECCA M.D. Director — 491 $431.94 $212,083
2026-03-04 SIBOLD WILLIAM JOHN Chief Executive Officer — 14,995 $0.00 $0
2026-03-04 DIER MARDI C Chief Financial Officer — 5,215 $0.00 $0
2026-03-04 SOERGEL DAVID M.D. Officer — 4,374 $0.00 $0
2026-03-04 HUNTSMAN CAROLE A Officer — 3,989 $0.00 $0
2026-03-04 KELLEY SHANNON T General Counsel — 4,017 $0.00 $0
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
958.40
+432.05%
180.13
0.00
0.00
Operating Revenue
958.40
+432.05%
180.13
0.00
0.00
Cost Of Revenue
56.15
+800.82%
6.23
0.00
0.00
Reconciled Cost Of Revenue
56.15
+800.82%
6.23
0.00
0.00
Gross Profit
902.25
+418.84%
173.90
0.00
0.00
Operating Expense
1,202.35
+78.98%
671.77
+76.55%
380.50
+29.61%
293.57
Research And Development
388.52
+64.13%
236.72
-13.08%
272.35
+10.96%
245.44
Selling General And Administration
813.83
+87.06%
435.06
+302.29%
108.15
+124.70%
48.13
General And Administrative Expense
—
—
108.15
+124.70%
48.13
Other Gand A
—
—
108.15
+124.70%
48.13
Total Expenses
1,258.50
+85.62%
678.01
+78.19%
380.50
+29.61%
293.57
Operating Income
-300.10
+39.72%
-497.88
-30.85%
-380.50
-29.61%
-293.57
Total Operating Income As Reported
-300.10
+39.72%
-497.88
-30.85%
-380.50
-29.61%
-293.57
EBITDA
-264.47
+41.25%
-450.12
-24.90%
-360.39
-23.88%
-290.92
Normalized EBITDA
-261.69
+41.86%
-450.12
-24.90%
-360.39
-23.88%
-290.92
Reconciled Depreciation
1.51
+37.41%
1.10
+107.97%
0.53
+12.85%
0.47
EBIT
-265.98
+41.05%
-451.22
-25.02%
-360.92
-23.86%
-291.39
Total Unusual Items
-2.78
0.00
0.00
—
Total Unusual Items Excluding Goodwill
-2.78
0.00
0.00
—
Special Income Charges
-2.78
0.00
0.00
—
Other Special Charges
2.78
—
—
—
Net Income
-288.28
+38.12%
-465.89
-24.69%
-373.63
-26.50%
-295.35
Pretax Income
-288.28
+38.12%
-465.89
-24.69%
-373.63
-26.50%
-295.35
Net Non Operating Interest Income Expense
15.05
-52.93%
31.98
+365.82%
6.87
+485.95%
-1.78
Interest Expense Non Operating
22.31
+52.06%
14.67
+15.41%
12.71
+220.69%
3.96
Net Interest Income
15.05
-52.93%
31.98
+365.82%
6.87
+485.95%
-1.78
Interest Expense
22.31
+52.06%
14.67
+15.41%
12.71
+220.69%
3.96
Interest Income Non Operating
37.36
-19.91%
46.65
+138.30%
19.58
+796.02%
2.19
Interest Income
37.36
-19.91%
46.65
+138.30%
19.58
+796.02%
2.19
Other Income Expense
-3.24
—
—
—
Other Non Operating Income Expenses
-0.46
—
—
—
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-288.28
+38.12%
-465.89
-24.69%
-373.63
-26.50%
-295.35
Net Income From Continuing Operation Net Minority Interest
-288.28
+38.12%
-465.89
-24.69%
-373.63
-26.50%
-295.35
Net Income From Continuing And Discontinued Operation
-288.28
+38.12%
-465.89
-24.69%
-373.63
-26.50%
-295.35
Normalized Income
-285.50
+38.72%
-465.89
-24.69%
-373.63
-26.50%
-295.35
Net Income Common Stockholders
-288.28
+38.12%
-465.89
-24.69%
-373.63
-26.50%
-295.35
Diluted EPS
-12.85
+41.32%
-21.90
-9.55%
-19.99
-16.02%
-17.23
Basic EPS
-12.85
+41.32%
-21.90
-9.55%
-19.99
-16.02%
-17.23
Basic Average Shares
22.43
+5.46%
21.27
+13.83%
18.69
+9.05%
17.14
Diluted Average Shares
22.43
+5.46%
21.27
+13.83%
18.69
+9.05%
17.14
Diluted NI Availto Com Stockholders
-288.28
+38.12%
-465.89
-24.69%
-373.63
-26.50%
-295.35
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
1,259.59
+20.85%
1,042.25
+62.71%
640.55
+76.67%
362.57
Current Assets
1,245.77
+20.61%
1,032.93
+62.08%
637.28
+76.35%
361.37
Cash Cash Equivalents And Short Term Investments
983.56
+6.19%
926.25
+46.07%
634.13
+76.75%
358.77
Cash And Cash Equivalents
198.69
+98.66%
100.02
+0.10%
99.92
-69.86%
331.55
Cash Equivalents
—
—
97.19
-69.29%
316.45
Cash Financial
—
—
2.73
-81.93%
15.10
Other Short Term Investments
784.87
-5.01%
826.23
+54.66%
534.22
+1862.23%
27.23
Receivables
134.48
+149.85%
53.82
0.00
—
Accounts Receivable
134.48
+149.85%
53.82
0.00
—
Inventory
74.84
+119.68%
34.07
0.00
—
Raw Materials
0.00
0.00
0.00
—
Work In Process
67.63
+129.01%
29.53
0.00
—
Finished Goods
7.21
+58.94%
4.54
0.00
—
Prepaid Assets
—
—
—
—
Restricted Cash
5.09
+1.80%
5.00
0.00
—
Other Current Assets
47.80
+246.76%
13.79
+337.65%
3.15
+21.39%
2.60
Total Non Current Assets
13.82
+48.27%
9.32
+185.36%
3.27
+171.49%
1.20
Net PPE
6.44
+40.23%
4.59
+40.57%
3.27
+171.49%
1.20
Gross PPE
6.44
+40.23%
4.59
+40.57%
3.27
+171.49%
1.20
Other Properties
6.44
+40.23%
4.59
+40.57%
3.27
+171.49%
1.20
Goodwill And Other Intangible Assets
7.38
+56.08%
4.73
0.00
—
Total Liabilities Net Minority Interest
656.90
+128.20%
287.86
+22.38%
235.21
+42.40%
165.18
Current Liabilities
310.29
+83.30%
169.28
+42.79%
118.55
+2.29%
115.89
Payables And Accrued Expenses
240.06
+80.04%
133.34
+32.03%
100.99
+0.56%
100.43
Payables
48.88
+12.11%
43.60
+55.48%
28.04
+17.67%
23.83
Accounts Payable
48.88
+12.11%
43.60
+55.48%
28.04
+17.67%
23.83
Current Accrued Expenses
191.18
+113.04%
89.74
+23.01%
72.95
-4.76%
76.60
Pensionand Other Post Retirement Benefit Plans Current
69.21
+97.99%
34.96
+105.27%
17.03
+14.57%
14.86
Current Debt And Capital Lease Obligation
1.02
+3.56%
0.98
+86.53%
0.53
-12.46%
0.60
Current Capital Lease Obligation
1.02
+3.56%
0.98
+86.53%
0.53
-12.46%
0.60
Total Non Current Liabilities Net Minority Interest
346.61
+192.28%
118.59
+1.65%
116.67
+136.70%
49.29
Long Term Debt And Capital Lease Obligation
346.61
+192.28%
118.59
+1.65%
116.67
+136.70%
49.29
Long Term Debt
339.88
+189.09%
117.57
+1.81%
115.48
+134.29%
49.29
Long Term Capital Lease Obligation
6.73
+561.20%
1.02
-14.17%
1.19
0.00
Stockholders Equity
602.69
-20.11%
754.38
+86.11%
405.33
+105.35%
197.39
Common Stock Equity
602.69
-20.11%
754.38
+86.11%
405.33
+105.35%
197.39
Capital Stock
0.00
+0.00%
0.00
+0.00%
0.00
+0.00%
0.00
Common Stock
0.00
+0.00%
0.00
+0.00%
0.00
+0.00%
0.00
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
22.84
+3.81%
22.00
+10.71%
19.88
+9.79%
18.10
Ordinary Shares Number
22.84
+3.81%
22.00
+10.71%
19.88
+9.79%
18.10
Additional Paid In Capital
2,692.28
+5.33%
2,556.09
+46.80%
1,741.15
+50.09%
1,160.08
Retained Earnings
-2,090.47
-16.00%
-1,802.18
-34.86%
-1,336.29
-38.81%
-962.66
Gains Losses Not Affecting Retained Earnings
0.87
+86.54%
0.47
+0.00%
0.47
+1562.50%
-0.03
Other Equity Adjustments
0.87
+86.54%
0.47
+0.00%
0.47
+1562.50%
-0.03
Total Equity Gross Minority Interest
602.69
-20.11%
754.38
+86.11%
405.33
+105.35%
197.39
Total Capitalization
942.57
+8.10%
871.95
+67.42%
520.81
+111.13%
246.68
Working Capital
935.48
+8.32%
863.65
+66.49%
518.73
+111.32%
245.47
Invested Capital
942.57
+8.10%
871.95
+67.42%
520.81
+111.13%
246.68
Total Debt
347.63
+190.73%
119.57
+2.03%
117.19
+134.90%
49.89
Net Debt
141.19
+704.49%
17.55
+12.75%
15.56
—
Capital Lease Obligations
7.75
+287.26%
2.00
+16.81%
1.71
+184.55%
0.60
Net Tangible Assets
595.31
-20.59%
749.65
+84.95%
405.33
+105.35%
197.39
Tangible Book Value
595.31
-20.59%
749.65
+84.95%
405.33
+105.35%
197.39
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-189.55
+58.39%
-455.57
-40.51%
-324.23
-44.19%
-224.86
Cash Flow From Continuing Operating Activities
-189.55
+58.39%
-455.57
-40.51%
-324.23
-44.19%
-224.86
Net Income From Continuing Operations
-288.28
+38.12%
-465.89
-24.69%
-373.63
-26.50%
-295.35
Depreciation Amortization Depletion
1.51
+37.41%
1.10
+107.97%
0.53
+12.85%
0.47
Depreciation And Amortization
1.51
+37.41%
1.10
+107.97%
0.53
+12.85%
0.47
Other Non Cash Items
4.81
+185.02%
1.69
-30.03%
2.41
+202.89%
0.80
Stock Based Compensation
98.13
+22.85%
79.88
+60.61%
49.73
+57.26%
31.62
Operating Gains Losses
2.78
—
—
—
Change In Working Capital
-8.50
+88.25%
-72.34
-2108.33%
-3.28
-108.71%
37.60
Change In Receivables
-80.65
-49.85%
-53.82
0.00
0.00
Changes In Account Receivables
-80.65
-49.85%
-53.82
0.00
0.00
Change In Inventory
-36.98
-8.54%
-34.07
0.00
0.00
Change In Prepaid Assets
-34.02
-219.84%
-10.64
-1816.40%
-0.56
+55.85%
-1.26
Change In Payables And Accrued Expense
143.15
+446.78%
26.18
+1062.18%
-2.72
-107.00%
38.86
Change In Accrued Expense
137.87
+1197.87%
10.62
+253.27%
-6.93
-119.04%
36.41
Change In Payable
5.28
-66.07%
15.56
+269.55%
4.21
+71.77%
2.45
Change In Account Payable
5.28
-66.07%
15.56
+269.55%
4.21
+71.77%
2.45
Investing Cash Flow
32.32
+111.78%
-274.39
+45.40%
-502.52
-343.13%
206.69
Cash Flow From Continuing Investing Activities
32.32
+111.78%
-274.39
+45.40%
-502.52
-343.13%
206.69
Net PPE Purchase And Sale
-0.47
+68.06%
-1.46
+1.15%
-1.48
-581.57%
-0.22
Purchase Of PPE
-0.47
+68.06%
-1.46
+1.15%
-1.48
-581.57%
-0.22
Capital Expenditure
-3.47
+46.35%
-6.46
-336.92%
-1.48
-581.57%
-0.22
Net Investment Purchase And Sale
35.79
+113.36%
-267.92
+46.53%
-501.04
-342.16%
206.90
Purchase Of Investment
-1,047.51
+7.40%
-1,131.21
-35.56%
-834.44
-481.58%
-143.48
Sale Of Investment
1,083.30
+25.49%
863.28
+158.93%
333.40
-4.85%
350.38
Net Intangibles Purchase And Sale
-3.00
+40.00%
-5.00
0.00
0.00
Purchase Of Intangibles
-3.00
+40.00%
-5.00
0.00
0.00
Financing Cash Flow
255.98
-65.18%
735.06
+23.52%
595.12
+89.86%
313.45
Cash Flow From Continuing Financing Activities
255.98
-65.18%
735.06
+23.52%
595.12
+89.86%
313.45
Net Issuance Payments Of Debt
228.34
0.00
-100.00%
65.00
+30.00%
50.00
Issuance Of Debt
350.00
0.00
-100.00%
65.00
+30.00%
50.00
Repayment Of Debt
-121.66
0.00
0.00
—
Long Term Debt Issuance
350.00
0.00
-100.00%
65.00
+30.00%
50.00
Long Term Debt Payments
-121.66
0.00
0.00
—
Net Long Term Debt Issuance
228.34
0.00
-100.00%
65.00
+30.00%
50.00
Net Common Stock Issuance
0.00
-100.00%
397.49
+52.77%
260.19
+1.88%
255.38
Proceeds From Stock Option Exercised
38.05
-88.73%
337.57
+24.89%
270.29
+2918.34%
8.96
Net Other Financing Charges
-10.41
—
-0.36
+59.03%
-0.89
Changes In Cash
98.75
+1834.78%
5.10
+102.20%
-231.63
-178.45%
295.28
Effect Of Exchange Rate Changes
0.01
0.00
0.00
—
Beginning Cash Position
105.02
+5.11%
99.92
-69.86%
331.55
+814.14%
36.27
End Cash Position
203.78
+94.04%
105.02
+5.11%
99.92
-69.86%
331.55
Free Cash Flow
-193.02
+58.22%
-462.03
-41.85%
-325.71
-44.71%
-225.07
Change In Interest Payable
5.97
+124.78%
-24.09
-342.06%
-5.45
-181566.67%
-0.00
Common Stock Issuance
0.00
-100.00%
397.49
+52.77%
260.19
+1.88%
255.38
Issuance Of Capital Stock
0.00
-100.00%
397.49
+52.77%
260.19
+1.88%
255.38
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

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