Symbols / PLRX Stock $1.26 +0.00% Pliant Therapeutics, Inc.

Healthcare • Biotechnology • United States • NMS
PLRX (Stock) Chart
O: — H: — L: — C: — V: —
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Stock Fundamentals
Scroll to Statements
Index EQUITY
Sector Healthcare
Industry Biotechnology
CEO Dr. Bernard Coulie M.B.A., M.D., Ph.D.
Exch · Country NMS · United States
Market Cap 78.01M
Enterprise Value -83.83M
Income -149.34M
Sales —
FCF (ttm) -84.56M
Book/sh 2.95
Cash/sh 3.08
Employees 49
Insider 10d —
IPO Jun 03, 2020
Div forward ($/yr)
Div TTM ($/yr)
Dividend Yield
Ex-Div Date
5Y Avg Yield
Yield vs 5Y Avg
Payout 0.00%
P/E —
Forward P/E -1.04
PEG —
P/S —
P/B 0.43
P/C —
EV/EBITDA 0.56
EV/Sales —
Quick Ratio 11.72
Current Ratio 12.00
Debt/Eq 16.06
LT Debt/Eq —
EPS (ttm) -2.43
EPS next Y -1.22
EPS Growth —
Revenue Growth —
EPS Gr Q/Q —
Rev Gr Q/Q —
Earnings (next) 2026-05-07
Earnings (prior) 2026-03-11
ROA -30.15%
ROE -61.55%
ROIC —
Gross Margin 0.00%
Oper. Margin 0.00%
Profit Margin 0.00%
Shs Outstand 61.91M
Shs Float 60.23M
Insider Own 2.35%
Instit Own 77.75%
Short Float 6.66%
Short Ratio 7.56
Short Interest 4.03M
52W High 1.95
vs 52W High -35.38%
52W Low 1.09
vs 52W Low 15.60%
Beta 1.25
Impl. Vol. 39.84%
Rel Volume 0.07
Avg Volume 665.35K
Volume 44.94K
Target (mean) $2.67
Tgt Median $3.00
Tgt Low $2.00
Tgt High $3.00
# Analysts 3
Recom None
Prev Close $1.26
Price $1.26
Change 0.00%
About

Pliant Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing integrin-based therapeutics for the treatment of solid tumors. The company's lead product candidate is the PLN-101095, an oral, small molecule dual inhibitor of avß8 and avß1 integrins that is in Phase 1a/1b for the treatment of solid tumors. It is also developing drug discovery platform comprising proprietary library of over 15,000 integrin binding molecules, focusing on integrin-based target-mediated drug delivery. Pliant Therapeutics, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.

Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$2.67
Mean price target
2. Current target
$1.26
Latest analyst target
3. DCF / Fair value
$-24.58
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$1.26
Low
$2.00
High
$3.00
Mean
$2.67

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-03-13 main Canaccord Genuity Hold → Hold $3
2026-03-12 main Piper Sandler Overweight → Overweight $3
2025-11-07 main RBC Capital Sector Perform → Sector Perform $2
2025-10-10 down JP Morgan Neutral → Underweight —
2025-08-08 main Piper Sandler Overweight → Overweight $4
2025-03-18 reit HC Wainwright & Co. Neutral → Neutral —
2025-03-04 reit HC Wainwright & Co. Neutral → Neutral —
2025-03-04 main Citigroup Neutral → Neutral $2
2025-03-04 main RBC Capital Sector Perform → Sector Perform $3
2025-03-04 main Wells Fargo Equal-Weight → Equal-Weight $3
2025-03-04 down Needham Buy → Hold $10
2025-03-03 down Leerink Partners Outperform → Market Perform $2
2025-02-14 reit HC Wainwright & Co. Neutral → Neutral —
2025-02-14 reit Needham Buy → Buy $10
2025-02-10 down JP Morgan Overweight → Neutral —
2025-02-10 down RBC Capital Outperform → Sector Perform $4
2025-02-10 down Canaccord Genuity Buy → Hold $4
2025-02-10 down Wells Fargo Overweight → Equal-Weight $4
2025-02-10 down Citigroup Buy → Neutral $4
2025-02-10 main Needham Buy → Buy $10
News
RSS: Latest PLRX news
Insider Transactions
Filed Date Insider Relationship Transaction Shares Price Value SEC
2026-01-20 COULIE BERNARD J Chief Executive Officer — 89,375 $1.28 $114,400
2026-01-20 CUMMINGS KEITH LAMONT Chief Financial Officer — 24,002 $1.28 $30,723
2026-01-20 CHEUNG LILY Officer — 7,534 $1.28 $9,644
2026-01-20 KUO MINNIE Chief Operating Officer — 6,917 $1.28 $8,854
2025-01-23 COULIE BERNARD J Chief Executive Officer — 162,500 $0.00 $0
2025-01-23 CUMMINGS KEITH LAMONT Chief Financial Officer — 56,650 $0.00 $0
2025-01-23 OUIMETTE MICHAEL General Counsel — 35,000 $0.00 $0
2025-01-23 CHEUNG LILY Officer — 25,875 $0.00 $0
2025-01-23 LEFEBVRE ERIC Officer — 45,650 $0.00 $0
2025-01-23 HULL JOHANNES P. Officer — 40,150 $0.00 $0
Financials
Statement View
Amounts in millions (2 decimals, no suffix) • EPS per share (2 decimals) • Trend = period evolution • YoY Growth = previous period %
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Revenue
0.00
0.00
-100.00%
1.58
-83.69%
9.69
Operating Revenue
0.00
0.00
-100.00%
1.58
-83.69%
9.69
Operating Expense
156.37
-31.52%
228.37
+22.96%
185.72
+35.68%
136.88
Research And Development
109.16
-35.53%
169.31
+32.48%
127.80
+31.84%
96.94
Selling General And Administration
47.22
-20.05%
59.05
+1.95%
57.93
+45.00%
39.95
General And Administrative Expense
47.22
-20.05%
59.05
+1.95%
57.93
+45.00%
39.95
Other Gand A
47.22
-20.05%
59.05
+1.95%
57.93
+45.00%
39.95
Total Expenses
156.37
-31.52%
228.37
+22.96%
185.72
+35.68%
136.88
Operating Income
-156.37
+31.52%
-228.37
-24.01%
-184.15
-44.77%
-127.20
Total Operating Income As Reported
-156.37
+31.52%
-228.37
-24.01%
-184.15
-44.77%
-127.20
EBITDA
-145.09
+29.28%
-205.16
-29.66%
-158.23
-31.08%
-120.71
Normalized EBITDA
-143.26
+30.17%
-205.16
-29.66%
-158.23
-31.08%
-120.71
Reconciled Depreciation
1.70
-20.19%
2.12
+15.43%
1.84
+0.99%
1.82
EBIT
-146.78
+29.19%
-207.28
-29.49%
-160.07
-30.64%
-122.53
Total Unusual Items
-1.83
0.00
—
—
Total Unusual Items Excluding Goodwill
-1.83
0.00
—
—
Special Income Charges
-1.83
0.00
—
—
Other Special Charges
1.83
—
—
—
Net Income
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Pretax Income
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Non Operating Interest Income Expense
8.86
-50.96%
18.06
-20.82%
22.81
+488.01%
3.88
Interest Expense Non Operating
2.56
-15.38%
3.02
+138.67%
1.27
+60.18%
0.79
Net Interest Income
8.86
-50.96%
18.06
-20.82%
22.81
+488.01%
3.88
Interest Expense
2.56
-15.38%
3.02
+138.67%
1.27
+60.18%
0.79
Interest Income Non Operating
11.42
-45.86%
21.09
-12.42%
24.08
+415.55%
4.67
Interest Income
11.42
-45.86%
21.09
-12.42%
24.08
+415.55%
4.67
Other Income Expense
-1.83
—
—
—
Tax Rate For Calcs
0.00
0.00
0.00
0.00
Tax Effect Of Unusual Items
0.00
0.00
0.00
0.00
Net Income Including Noncontrolling Interests
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Income From Continuing Operation Net Minority Interest
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Income From Continuing And Discontinued Operation
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Income Continuous Operations
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Normalized Income
-147.52
+29.86%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Net Income Common Stockholders
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Diluted EPS
-2.43
+29.97%
-3.47
-26.18%
-2.75
+6.46%
-2.94
Basic EPS
-2.43
+29.97%
-3.47
-26.18%
-2.75
+6.46%
-2.94
Basic Average Shares
61.37
+1.37%
60.54
+3.10%
58.72
+39.75%
42.02
Diluted Average Shares
61.37
+1.37%
60.54
+3.10%
58.72
+39.75%
42.02
Diluted NI Availto Com Stockholders
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Total Other Finance Cost
—
—
—
—
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Total Assets
225.23
-43.26%
396.95
-22.49%
512.15
+46.07%
350.61
Current Assets
196.45
-45.77%
362.26
-28.34%
505.50
+48.54%
340.31
Cash Cash Equivalents And Short Term Investments
190.94
-46.32%
355.72
-28.03%
494.25
+49.23%
331.19
Cash And Cash Equivalents
45.45
-36.16%
71.19
+12.58%
63.23
+87.72%
33.69
Other Short Term Investments
145.50
-48.86%
284.54
-33.98%
431.01
+44.88%
297.50
Receivables
0.82
-64.25%
2.30
-23.19%
3.00
-4.68%
3.14
Accounts Receivable
—
—
0.00
-100.00%
1.98
Taxes Receivable
—
—
0.00
-100.00%
0.08
Accrued Interest Receivable
0.82
-64.25%
2.30
-23.19%
3.00
+178.01%
1.08
Prepaid Assets
3.55
-12.91%
4.08
-41.69%
6.99
+20.34%
5.81
Assets Held For Sale Current
1.04
0.00
—
—
Other Current Assets
0.09
-43.56%
0.16
-87.19%
1.27
+635.26%
0.17
Total Non Current Assets
28.78
-17.02%
34.69
+421.42%
6.65
-35.43%
10.30
Net PPE
26.91
-17.89%
32.77
+585.81%
4.78
-51.78%
9.91
Gross PPE
37.77
-13.31%
43.58
+223.74%
13.46
-19.64%
16.75
Accumulated Depreciation
-10.87
-0.57%
-10.81
-24.48%
-8.68
-26.91%
-6.84
Properties
0.00
0.00
0.00
0.00
Machinery Furniture Equipment
2.94
+1.98%
2.88
+2222.58%
0.12
+313.33%
0.03
Construction In Progress
0.15
-55.78%
0.35
+565.38%
0.05
-21.21%
0.07
Other Properties
32.53
-14.91%
38.23
+228.98%
11.62
-22.54%
15.00
Leases
2.16
+1.79%
2.12
+27.36%
1.66
+0.79%
1.65
Other Non Current Assets
1.87
-2.24%
1.92
+2.29%
1.87
+375.63%
0.39
Total Liabilities Net Minority Interest
44.02
-52.60%
92.87
+140.73%
38.58
+3.51%
37.27
Current Liabilities
16.36
-50.73%
33.22
+16.46%
28.52
+19.28%
23.91
Payables And Accrued Expenses
6.62
-69.24%
21.52
+18.49%
18.16
+27.41%
14.26
Payables
0.48
-91.95%
5.96
+31.54%
4.53
+186.77%
1.58
Accounts Payable
0.48
-91.95%
5.96
+31.54%
4.53
+186.77%
1.58
Current Accrued Expenses
6.14
-60.54%
15.56
+14.15%
13.63
+7.55%
12.68
Pensionand Other Post Retirement Benefit Plans Current
8.30
-25.61%
11.15
+23.36%
9.04
+25.58%
7.20
Current Debt And Capital Lease Obligation
1.45
+166.97%
0.54
-58.88%
1.32
-46.36%
2.46
Current Capital Lease Obligation
1.45
+166.97%
0.54
-58.88%
1.32
-46.36%
2.46
Current Deferred Liabilities
—
—
—
—
Total Non Current Liabilities Net Minority Interest
27.66
-53.63%
59.65
+493.30%
10.05
-24.73%
13.36
Long Term Debt And Capital Lease Obligation
27.66
-53.63%
59.65
+493.30%
10.05
-24.73%
13.36
Long Term Debt
—
30.21
+200.49%
10.05
+1.26%
9.93
Long Term Capital Lease Obligation
27.66
-6.05%
29.44
0.00
-100.00%
3.43
Non Current Deferred Liabilities
—
—
—
—
Stockholders Equity
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Common Stock Equity
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Capital Stock
0.01
+0.00%
0.01
+0.00%
0.01
+20.00%
0.01
Common Stock
0.01
+0.00%
0.01
+0.00%
0.01
+20.00%
0.01
Preferred Stock
0.00
0.00
0.00
0.00
Share Issued
61.45
+0.97%
60.86
+1.57%
59.92
+22.43%
48.94
Ordinary Shares Number
61.45
+0.97%
60.86
+1.57%
59.92
+22.43%
48.94
Additional Paid In Capital
1,040.61
+2.64%
1,013.81
+4.20%
972.97
+48.84%
653.71
Retained Earnings
-859.40
-21.03%
-710.05
-42.08%
-499.75
-47.67%
-338.41
Gains Losses Not Affecting Retained Earnings
-0.01
-104.67%
0.32
-6.96%
0.34
+117.62%
-1.96
Other Equity Adjustments
-0.01
-104.67%
0.32
-6.96%
0.34
+117.62%
-1.96
Total Equity Gross Minority Interest
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Total Capitalization
181.21
-45.79%
334.29
-30.88%
483.63
+49.61%
323.27
Working Capital
180.08
-45.27%
329.05
-31.01%
476.98
+50.75%
316.40
Invested Capital
181.21
-45.79%
334.29
-30.88%
483.63
+49.61%
323.27
Total Debt
29.11
-51.65%
60.19
+429.30%
11.37
-28.09%
15.81
Capital Lease Obligations
29.11
-2.92%
29.98
+2174.73%
1.32
-77.61%
5.89
Net Tangible Assets
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Tangible Book Value
181.21
-40.41%
304.08
-35.79%
473.58
+51.14%
313.34
Line Item Trend 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Operating Cash Flow
-128.34
+17.47%
-155.50
-33.64%
-116.36
-22.96%
-94.63
Cash Flow From Continuing Operating Activities
-128.34
+17.47%
-155.50
-33.64%
-116.36
-22.96%
-94.63
Net Income From Continuing Operations
-149.34
+28.99%
-210.30
-30.35%
-161.34
-30.83%
-123.32
Depreciation Amortization Depletion
1.70
-20.19%
2.12
+15.43%
1.84
+0.99%
1.82
Depreciation
1.70
-20.19%
2.12
+15.43%
1.84
+0.99%
1.82
Depreciation And Amortization
1.70
-20.19%
2.12
+15.43%
1.84
+0.99%
1.82
Other Non Cash Items
3.28
-5.04%
3.45
+44.39%
2.39
+28.63%
1.86
Stock Based Compensation
26.23
-30.28%
37.63
-15.41%
44.48
+96.84%
22.60
Operating Gains Losses
1.78
—
—
—
Gain Loss On Sale Of PPE
-0.04
0.00
—
—
Change In Working Capital
-15.94
-275.37%
9.09
+626.54%
1.25
-70.33%
4.22
Change In Receivables
—
0.00
-100.00%
1.98
+13120.00%
0.01
Changes In Account Receivables
—
0.00
-100.00%
1.98
+13120.00%
0.01
Change In Prepaid Assets
2.54
-46.13%
4.72
+226.29%
-3.73
-1170.41%
-0.29
Change In Payables And Accrued Expense
-17.65
-437.10%
5.24
-8.96%
5.75
-12.25%
6.55
Change In Accrued Expense
-12.17
-419.60%
3.81
+36.89%
2.78
-64.82%
7.90
Change In Payable
-5.48
-483.75%
1.43
-51.90%
2.97
+319.76%
-1.35
Change In Account Payable
-5.48
-483.75%
1.43
-51.90%
2.97
+319.76%
-1.35
Change In Other Current Assets
0.04
+200.00%
-0.04
0.00
-100.00%
0.20
Change In Other Current Liabilities
-0.88
-6.83%
-0.82
+70.15%
-2.75
-21.66%
-2.26
Investing Cash Flow
134.29
-4.31%
140.34
+210.49%
-127.01
+15.44%
-150.20
Cash Flow From Continuing Investing Activities
134.29
-4.31%
140.34
+210.49%
-127.01
+15.44%
-150.20
Net PPE Purchase And Sale
-0.22
+94.31%
-3.85
-317.81%
-0.92
+47.67%
-1.76
Purchase Of PPE
-0.37
+90.28%
-3.85
-317.81%
-0.92
+47.67%
-1.76
Sale Of PPE
0.15
0.00
—
—
Capital Expenditure
-0.37
+90.28%
-3.85
-317.81%
-0.92
+47.67%
-1.76
Net Investment Purchase And Sale
134.51
-6.71%
144.19
+214.35%
-126.09
+15.06%
-148.44
Purchase Of Investment
-203.40
+3.73%
-211.28
+63.76%
-583.07
-79.01%
-325.72
Sale Of Investment
337.91
-4.94%
355.47
-22.21%
456.98
+157.78%
177.27
Financing Cash Flow
-31.70
-237.12%
23.12
-91.58%
274.40
+20.96%
226.85
Cash Flow From Continuing Financing Activities
-31.70
-237.12%
23.12
-91.58%
274.40
+20.96%
226.85
Net Issuance Payments Of Debt
-32.27
-262.06%
19.91
0.00
-100.00%
9.85
Issuance Of Debt
0.00
-100.00%
19.91
0.00
-100.00%
9.85
Repayment Of Debt
-32.27
0.00
—
—
Long Term Debt Issuance
0.00
-100.00%
19.91
0.00
-100.00%
9.85
Long Term Debt Payments
-32.27
0.00
—
—
Net Long Term Debt Issuance
-32.27
-262.06%
19.91
0.00
-100.00%
9.85
Net Common Stock Issuance
0.57
-82.23%
3.21
-98.83%
275.25
+26.52%
217.56
Net Other Financing Charges
—
—
-0.85
-52.06%
-0.56
Changes In Cash
-25.74
-423.65%
7.95
-74.37%
31.03
+272.58%
-17.98
Beginning Cash Position
72.67
+12.29%
64.72
+92.13%
33.68
-34.80%
51.66
End Cash Position
46.93
-35.42%
72.67
+12.29%
64.72
+92.13%
33.68
Free Cash Flow
-128.71
+19.23%
-159.35
-35.87%
-117.28
-21.67%
-96.39
Interest Paid Supplemental Data
2.54
-3.09%
2.62
+128.02%
1.15
+86.83%
0.61
Amortization Of Securities
3.96
+57.61%
2.51
+150.30%
-4.99
-176.30%
-1.81
Common Stock Issuance
0.57
-82.23%
3.21
-98.83%
275.25
+26.52%
217.56
Issuance Of Capital Stock
0.57
-82.23%
3.21
-98.83%
275.25
+26.52%
217.56
Net Preferred Stock Issuance
—
—
—
—
Preferred Stock Issuance
—
—
—
—
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Trades
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