PRQR Chart
About

ProQR Therapeutics N.V., a biotechnology company, focuses on the discovery and development of novel therapeutic medicines. The company's products pipeline includes AX-0810 for cholestatic diseases targeting Na-taurocholate cotransporting polypeptide (NTCP); and AX-1412 for cardiovascular diseases (CVDs) targeting Beta-1,4-galactosyltransferase 1 (B4GALT1). It also develops various other early-stage research programs, including AX-1005 for undisclosed targets in CVDs; AX-2402, which focuses on Rett syndrome; AX-2911 for metabolic dysfunction-associated steatohepatitis (MASH) targeting patatin-like phospholipase domain-containing protein 3 (PNPLA3); AX-0601 for obesity and Type 2 diabetes; and AX-9115 for rare metabolic condition, as well as additional programs in Rett Syndrome, additional CNS programs, and multiple other unnamed targets and programs. In addition, the company develops Axiomer RNA base-editing platform technology. It has a license agreement with Radboud University Medical Center; Inserm Transfert SA; Ionis Pharmaceuticals, Inc.; Vico Therapeutics B.V.; University of Rochester; and Leiden University Medical Center, as well as license and research collaboration with Eli Lilly and Company for the discovery, development, and commercialization of potential new medicines for genetic disorders in the liver and nervous system. The company was incorporated in 2012 and is headquartered in Leiden, the Netherlands.

Fundamentals
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Sector Healthcare Industry Biotechnology Market Cap 162.23M
Enterprise Value 71.84M Income -42.57M Sales 16.07M
Book/sh 0.64 Cash/sh 1.01 Dividend Yield —
Payout 0.00% Employees 166 IPO —
P/E — Forward P/E -3.28 PEG —
P/S 10.09 P/B 2.41 P/C —
EV/EBITDA -1.65 EV/Sales 4.47 Quick Ratio 3.30
Current Ratio 3.36 Debt/Eq 28.90 LT Debt/Eq —
EPS (ttm) -0.48 EPS next Y -0.47 EPS Growth —
Revenue Growth -26.80% Earnings 2026-03-12 ROA -24.02%
ROE -103.76% ROIC — Gross Margin 100.00%
Oper. Margin -3.87% Profit Margin -264.83% Shs Outstand 105.35M
Shs Float 64.36M Short Float 2.38% Short Ratio 3.39
Short Interest — 52W High 3.10 52W Low 1.07
Beta 0.20 Avg Volume 525.39K Volume 166.23K
Target Price $8.88 Recom Strong_buy Prev Close $1.51
Price $1.54 Change 1.99%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$8.88
Mean price target
2. Current target
$1.54
Latest analyst target
3. DCF / Fair value
$-5.39
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$1.54
Low
$4.00
High
$14.00
Mean
$8.88

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2025-11-04 main Chardan Capital Buy → Buy $4
2025-08-08 main Chardan Capital Buy → Buy $4
2025-06-27 reit Cantor Fitzgerald Overweight → Overweight $8
2025-06-27 reit JMP Securities Market Outperform → Market Outperform $8
2025-05-13 main Oppenheimer Outperform → Outperform $9
2025-04-29 init Evercore ISI Group — → Outperform $5
2025-03-14 main Chardan Capital Buy → Buy $4
2025-03-14 main HC Wainwright & Co. Buy → Buy $12
2025-02-12 init Jones Trading — → Buy $11
2024-12-12 reit JMP Securities Market Outperform → Market Outperform $8
2024-12-12 main Chardan Capital Buy → Buy $4
2024-12-12 reit HC Wainwright & Co. Buy → Buy $10
2024-11-08 main HC Wainwright & Co. Buy → Buy $10
2024-10-29 up Raymond James Outperform → Strong Buy $14
2024-05-10 main Chardan Capital Buy → Buy $3
2024-05-10 reit HC Wainwright & Co. Buy → Buy $5
2024-04-18 main Citigroup Neutral → Neutral $2
2024-03-14 reit HC Wainwright & Co. Buy → Buy $5
2024-03-14 main Chardan Capital Buy → Buy $3
2023-11-08 main Raymond James Outperform → Outperform $4
Insider Transactions

No recent insider transactions.

Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems-49.0013.90K707.07K546.75K
TaxRateForCalcs0.010.000.210.27
NormalizedEBITDA-24.11M-28.73M-59.83M-56.97M
TotalUnusualItems-7.00K4.63M3.37M2.02M
TotalUnusualItemsExcludingGoodwill-7.00K4.63M3.37M2.02M
NetIncomeFromContinuingOperationNetMinorityInterest-27.76M-28.12M-64.42M-60.74M
ReconciledDepreciation2.76M2.51M2.52M2.33M
EBITDA-24.12M-24.10M-56.46M-54.95M
EBIT-26.88M-26.61M-58.98M-57.28M
NetInterestIncome2.17M1.39M-5.02M-3.40M
InterestExpense1.08M1.20M5.13M3.40M
InterestIncome3.25M2.59M106.00K5.00K
NormalizedIncome-27.76M-32.74M-67.08M-62.22M
NetIncomeFromContinuingAndDiscontinuedOperation-27.76M-28.12M-64.42M-60.74M
TotalExpenses49.38M41.30M68.75M58.55M
TotalOperatingIncomeAsReported-30.47M-31.86M-65.16M-57.21M
DilutedAverageShares86.09M81.01M71.64M64.18M
BasicAverageShares86.09M81.01M71.64M64.18M
DilutedEPS-0.32-0.35-0.90-0.96
BasicEPS-0.32-0.35-0.90-0.96
DilutedNIAvailtoComStockholders-27.76M-28.12M-64.42M-60.74M
NetIncomeCommonStockholders-27.76M-28.12M-64.42M-60.74M
NetIncome-27.76M-28.12M-64.42M-60.74M
MinorityInterests0.00-384.00K-220.00K59.00K
NetIncomeIncludingNoncontrollingInterests-27.76M-27.73M-64.20M-60.80M
NetIncomeContinuousOperations-27.76M-27.73M-64.20M-60.80M
TaxProvision-197.00K-78.00K96.00K117.00K
PretaxIncome-27.96M-27.81M-64.11M-60.68M
OtherIncomeExpense338.00K5.59M6.07M-72.00K
OtherNonOperatingIncomeExpenses345.00K953.00K2.71M-1.88M
SpecialIncomeCharges0.004.89M-1.39M514.00K
GainOnSaleOfPPE0.002.93M0.000.00
GainOnSaleOfBusiness0.0092.00K0.00514.00K
OtherSpecialCharges-1.87M1.39M
EarningsFromEquityInterest0.000.00-8.00K-217.00K
GainOnSaleOfSecurity-7.00K-255.00K4.76M1.51M
NetNonOperatingInterestIncomeExpense2.17M1.39M-5.02M-3.40M
InterestExpenseNonOperating1.08M1.20M5.13M3.40M
InterestIncomeNonOperating3.25M2.59M106.00K5.00K
OperatingIncome-30.47M-34.79M-65.16M-57.21M
OperatingExpense49.38M41.30M68.75M58.55M
OtherOperatingExpenses-640.00K-80.00K-765.00K-1.04M
ResearchAndDevelopment36.36M25.15M50.87M42.22M
SellingGeneralAndAdministration13.66M16.24M18.65M17.37M
GeneralAndAdministrativeExpense13.66M16.24M18.65M17.37M
OtherGandA13.66M16.24M18.65M17.37M
TotalRevenue18.91M6.51M3.59M1.33M
OperatingRevenue18.91M6.51M3.59M1.33M
Line Item2024-12-312023-12-312022-12-312021-12-31
TreasurySharesNumber2.50M2.89M3.43M3.57M
OrdinarySharesNumber105.21M81.35M80.82M71.29M
ShareIssued107.71M84.25M84.25M74.87M
TotalDebt17.22M19.73M21.97M60.37M
TangibleBookValue88.56M41.39M67.06M113.83M
InvestedCapital93.14M45.68M73.84M157.92M
WorkingCapital114.94M86.78M133.47M163.89M
NetTangibleAssets88.56M41.39M67.06M113.83M
CapitalLeaseObligations12.63M15.44M15.20M16.28M
CommonStockEquity88.56M41.39M67.06M113.83M
TotalCapitalization88.56M45.68M71.34M153.15M
TotalEquityGrossMinorityInterest88.56M41.39M66.68M113.23M
MinorityInterest0.000.00-384.00K-604.00K
StockholdersEquity88.56M41.39M67.06M113.83M
GainsLossesNotAffectingRetainedEarnings27.60M25.98M30.26M30.30M
RetainedEarnings-427.16M-400.85M-379.11M-317.77M
AdditionalPaidInCapital483.81M412.89M412.54M398.31M
CapitalStock4.31M3.37M3.37M3.00M
CommonStock4.31M3.37M3.37M3.00M
TotalLiabilitiesNetMinorityInterest79.40M96.49M104.64M96.35M
TotalNonCurrentLiabilitiesNetMinorityInterest40.50M62.29M83.65M68.75M
NonCurrentDeferredLiabilities29.43M44.17M65.57M14.69M
NonCurrentDeferredRevenue29.43M44.17M65.57M14.69M
LongTermDebtAndCapitalLeaseObligation11.07M18.12M18.08M54.07M
LongTermCapitalLeaseObligation11.07M13.83M13.81M14.75M
LongTermDebt4.29M4.27M39.32M
CurrentLiabilities38.90M34.20M20.99M27.60M
OtherCurrentLiabilities9.32M8.82M9.95M14.76M
CurrentDeferredLiabilities21.94M20.57M5.64M5.12M
CurrentDeferredRevenue21.94M20.57M5.64M5.12M
CurrentDebtAndCapitalLeaseObligation6.15M1.61M3.89M6.30M
CurrentCapitalLeaseObligation1.57M1.61M1.39M1.53M
CurrentDebt4.58M2.50M4.77M
OtherCurrentBorrowings4.58M2.50M4.77M
PensionandOtherPostRetirementBenefitPlansCurrent0.00
PayablesAndAccruedExpenses1.49M3.20M1.51M1.42M
Payables1.49M3.20M1.51M1.42M
TotalTaxPayable1.48M1.66M1.12M1.23M
AccountsPayable16.00K1.54M392.00K191.00K
TotalAssets167.96M137.88M171.32M209.58M
TotalNonCurrentAssets14.11M16.90M16.86M18.10M
InvestmentsAndAdvances0.000.00621.00K629.00K
InvestmentinFinancialAssets0.000.00621.00K621.00K
LongTermEquityInvestment0.008.00K
InvestmentsinAssociatesatCost0.008.00K
NetPPE14.11M16.90M16.24M17.47M
AccumulatedDepreciation-17.96M-15.20M-12.87M-10.35M
GrossPPE32.07M32.09M29.11M27.82M
OtherProperties8.28M7.32M6.25M5.59M
Properties23.79M24.77M22.86M22.23M
CurrentAssets153.84M120.99M154.46M191.48M
PrepaidAssets2.41M793.00K2.45M3.14M
Receivables2.03M1.27M57.24M823.00K
OtherReceivables1.34M745.00K56.63M268.00K
TaxesReceivable690.00K523.00K607.00K555.00K
CashCashEquivalentsAndShortTermInvestments149.41M118.92M94.78M187.52M
CashAndCashEquivalents149.41M118.92M94.78M187.52M
CashEquivalents75.21M59.15M0.00
CashFinancial74.20M59.77M94.78M187.52M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-37.81M20.18M-69.22M-26.50M
RepaymentOfDebt-1.58M-2.63M-45.05M-820.00K
IssuanceOfDebt0.000.0027.66M
IssuanceOfCapitalStock71.64M0.0014.12M108.48M
CapitalExpenditure-1.42M-1.37M-708.00K-484.00K
EndCashPosition149.41M118.92M94.78M187.52M
BeginningCashPosition118.92M94.78M187.52M75.84M
EffectOfExchangeRateChanges673.00K599.00K7.35M1.29M
ChangesInCash29.81M23.55M-100.10M110.39M
FinancingCashFlow70.28M-2.27M-30.89M136.83M
CashFlowFromContinuingFinancingActivities70.28M-2.27M-30.89M136.83M
ProceedsFromStockOptionExercised223.00K354.00K34.00K1.52M
NetCommonStockIssuance71.64M0.0014.12M108.48M
CommonStockIssuance71.64M0.0014.12M108.48M
NetIssuancePaymentsOfDebt-1.58M-2.63M-45.05M26.84M
NetLongTermDebtIssuance-1.58M-2.63M-45.05M26.84M
LongTermDebtPayments-1.58M-2.63M-45.05M-820.00K
LongTermDebtIssuance0.000.0027.66M
InvestingCashFlow-4.07M4.28M-702.00K-425.00K
CashFlowFromContinuingInvestingActivities-4.07M4.28M-702.00K-425.00K
NetOtherInvestingChanges-2.65M-2.35M
NetInvestmentPurchaseAndSale0.000.000.00
SaleOfInvestment17.00M0.000.00
PurchaseOfInvestment-17.00M0.000.00
NetIntangiblesPurchaseAndSale0.007.94M0.000.00
SaleOfIntangibles0.007.94M0.000.00
NetPPEPurchaseAndSale-1.42M-1.31M-702.00K-425.00K
SaleOfPPE0.0060.00K6.00K59.00K
PurchaseOfPPE-1.42M-1.37M-708.00K-484.00K
OperatingCashFlow-36.39M21.55M-68.51M-26.01M
CashFlowFromContinuingOperatingActivities-36.39M21.55M-68.51M-26.01M
TaxesRefundPaid197.00K78.00K-96.00K-117.00K
InterestReceivedCFO3.25M2.59M106.00K5.00K
InterestPaidCFO-770.00K-789.00K-3.76M-2.25M
ChangeInWorkingCapital-13.26M48.96M-4.99M25.01M
ChangeInOtherWorkingCapital-13.26M48.96M-4.99M25.01M
OtherNonCashItems-2.81M-6.01M1.65M1.89M
StockBasedCompensation2.54M3.11M2.87M6.22M
DeferredTax-197.00K-78.00K96.00K117.00K
DeferredIncomeTax-197.00K-78.00K96.00K117.00K
DepreciationAmortizationDepletion2.76M2.51M2.52M2.33M
DepreciationAndAmortization2.76M2.51M2.52M2.33M
Depreciation2.76M2.51M2.52M2.33M
OperatingGainsLosses-345.00K-1.08M-2.71M1.58M
EarningsLossesFromEquityInvestments0.000.008.00K217.00K
GainLossOnInvestmentSecurities-345.00K-953.00K-2.71M1.88M
GainLossOnSaleOfBusiness0.00-131.00K0.00-514.00K
NetIncomeFromContinuingOperations-27.76M-27.73M-64.20M-60.80M
SEC Filings

No SEC filings found for this symbol (may be non-US or ticker not in SEC index).

Public Trades for PRQR
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