Symbols / SYBX
SYBX Chart
About
Synlogic, Inc., a biopharmaceutical company, engages in the discovery and development of synthetic biotics to treat metabolic diseases in the United States. Its pipeline include SYNB1618 for the treatment of phenylketonuria; SYNB1353, an orally administered, non-systemically absorbed drug candidate, which is in Phase I clinical to treat homocystinuria; SYNB8802, an orally administered, non-systemically absorbed drug candidate for the treatment of enteric hyperoxaluria; and SYNB2081 to lower uric acid for the potential treatment of gout. The company has a collaboration agreement with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; and Ginkgo Bioworks, Inc. Synlogic, Inc. is based in Winchester, Massachusetts.
Fundamentals
Scroll to Statements| Sector | Healthcare | Industry | Biotechnology | Market Cap | 7.27M |
| Enterprise Value | -8.32M | Income | -3.23M | Sales | — |
| Book/sh | 0.88 | Cash/sh | 1.33 | Dividend Yield | — |
| Payout | 0.00% | Employees | 1 | IPO | — |
| P/E | — | Forward P/E | -1.32 | PEG | — |
| P/S | inf | P/B | 0.70 | P/C | — |
| EV/EBITDA | 2.31 | EV/Sales | — | Quick Ratio | 2.50 |
| Current Ratio | 2.65 | Debt/Eq | — | LT Debt/Eq | — |
| EPS (ttm) | -0.26 | EPS next Y | -0.47 | EPS Growth | — |
| Revenue Growth | — | Earnings | 2025-03-06 16:00 | ROA | -12.94% |
| ROE | -27.54% | ROIC | — | Gross Margin | 0.00% |
| Oper. Margin | 0.00% | Profit Margin | 0.00% | Shs Outstand | 11.70M |
| Shs Float | 4.07M | Short Float | 0.20% | Short Ratio | 0.15 |
| Short Interest | — | 52W High | 1.96 | 52W Low | 0.54 |
| Beta | 0.53 | Avg Volume | 112.66K | Volume | 3.00K |
| Target Price | — | Recom | None | Prev Close | $0.62 |
| Price | $0.62 | Change | 0.24% |
Valuation Models
Price estimates from analyst targets and simple models.
1. Analyst consensus
—
Mean price target
2. Current target
$0.62
Latest analyst target
3. DCF / Fair value
$-8.25
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$0.62
Low
—
High
—
Mean
—
Latest analyst rating changes
| Date | Action | Analyst | Rating Change | Price Target |
|---|---|---|---|---|
| 2024-03-20 | up | HC Wainwright & Co. | Sell → Neutral | — |
| 2024-02-09 | down | Chardan Capital | Buy → Neutral | — |
| 2024-02-09 | down | Leerink Partners | Outperform → Market Perform | $1 |
| 2024-02-09 | down | HC Wainwright & Co. | Buy → Sell | — |
| 2023-12-11 | init | Alliance Global Partners | — → Buy | $30 |
- Will SYBX stock benefit from green energy trends - Trade Signal Summary & Weekly Top Performers Watchlists - mfd.ru Sun, 15 Feb 2026 10
- Synlogic to Delist from Nasdaq and Move to OTC - TipRanks ue, 20 Jan 2026 08
- Companies Like Synlogic (NASDAQ:SYBX) Are In A Position To Invest In Growth - simplywall.st hu, 18 Sep 2025 07
- Will SYBX stock continue upward momentum - Exit Point & Fast Moving Stock Trade Plans - mfd.ru Fri, 13 Feb 2026 05
- Synlogic Received Notice of Delisting - TradingView ue, 20 Jan 2026 08
- Will SYBX stock benefit from automation - Quarterly Trade Summary & Expert Approved Momentum Ideas - mfd.ru Sat, 14 Feb 2026 04
- Why Is Synlogic (SYBX) Stock Down 55% Today? - InvestorPlace Fri, 09 Feb 2024 08
- Will SYBX stock continue upward momentum - 2025 Short Interest & AI Driven Price Predictions - mfd.ru Mon, 09 Feb 2026 15
- Why Is Synlogic (SYBX) Stock Down 6% Today? - InvestorPlace hu, 28 Sep 2023 07
- Synlogic (SYBX) Stock Price, News & Analysis - MarketBeat hu, 31 Aug 2017 18
- Will SYBX stock attract ESG investors - GDP Growth & Long-Term Safe Investment Ideas - mfd.ru hu, 12 Feb 2026 02
Insider Transactions
| Date | Shares | Value | Url | Text | Insider | Position | Transaction | Start Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|
| 0 | 157 | 284 | — | Sale at price 1.81 per share. | DOOLEY MARY BETH | Chief Executive Officer | — | 2025-10-29 00:00:00 | D |
| 1 | 15000 | — | — | Stock Award(Grant) at price 0.00 per share. | FLYNN JAMES P | Director | — | 2025-04-25 00:00:00 | D |
| 2 | 15000 | — | — | Stock Award(Grant) at price 0.00 per share. | SHEA RICHARD P. | Director | — | 2025-04-25 00:00:00 | D |
| 3 | 144 | 173 | — | Sale at price 1.20 per share. | DOOLEY MARY BETH | Officer | — | 2025-04-02 00:00:00 | D |
| 4 | 2107 | 2802 | — | Sale at price 1.33 per share. | DOOLEY MARY BETH | Chief Executive Officer | — | 2025-02-03 00:00:00 | D |
| 5 | 79 | 111 | — | Sale at price 1.40 per share. | DOOLEY MARY BETH | Officer | — | 2024-10-29 00:00:00 | D |
| 6 | 372 | 644 | — | Sale at price 1.73 per share. | AWAD ANTOINE | Chief Operating Officer | — | 2024-04-02 00:00:00 | D |
| 7 | 188 | 325 | — | Sale at price 1.73 per share. | DOOLEY MARY BETH | Officer | — | 2024-04-02 00:00:00 | D |
Financials
| Line Item | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|
| TaxEffectOfUnusualItems | 0.00 | 0.00 | 0.00 | 0.00 |
| TaxRateForCalcs | 0.00 | 0.00 | 0.00 | 0.00 |
| NormalizedEBITDA | -14.01M | -51.65M | -63.62M | -58.12M |
| TotalUnusualItems | -9.00M | -7.65M | ||
| TotalUnusualItemsExcludingGoodwill | -9.00M | -7.65M | ||
| NetIncomeFromContinuingOperationNetMinorityInterest | -23.36M | -61.27M | -66.15M | -60.56M |
| ReconciledDepreciation | 347.00K | 1.96M | 2.52M | 2.44M |
| EBITDA | -23.01M | -59.30M | -63.62M | -58.12M |
| EBIT | -23.35M | -61.26M | -66.14M | -60.56M |
| NetInterestIncome | 1.43M | 2.47M | 1.26M | 208.00K |
| InterestExpense | 0.00 | 1.00K | 2.00K | 2.00K |
| InterestIncome | 1.43M | 2.47M | 1.27M | 210.00K |
| NormalizedIncome | -14.36M | -53.62M | -66.15M | -60.56M |
| NetIncomeFromContinuingAndDiscontinuedOperation | -23.36M | -61.27M | -66.15M | -60.56M |
| TotalExpenses | 15.79M | 58.53M | 68.60M | 62.52M |
| TotalOperatingIncomeAsReported | -40.95M | -55.16M | -67.42M | -60.77M |
| DilutedAverageShares | 12.20M | 6.50M | 4.78M | 3.69M |
| BasicAverageShares | 12.20M | 6.50M | 4.78M | 3.69M |
| DilutedEPS | -1.92 | -9.42 | -13.83 | -16.35 |
| BasicEPS | -1.92 | -9.42 | -13.83 | -16.35 |
| DilutedNIAvailtoComStockholders | -23.36M | -61.27M | -66.15M | -60.56M |
| NetIncomeCommonStockholders | -23.36M | -61.27M | -66.15M | -60.56M |
| NetIncome | -23.36M | -61.27M | -66.15M | -60.56M |
| NetIncomeIncludingNoncontrollingInterests | -23.36M | -61.27M | -66.15M | -60.56M |
| NetIncomeContinuousOperations | -23.36M | -61.27M | -66.15M | -60.56M |
| TaxProvision | 5.00K | 14.00K | 0.00 | |
| PretaxIncome | -23.35M | -61.26M | -66.15M | -60.56M |
| OtherIncomeExpense | -9.00M | -8.57M | 7.00K | -4.00K |
| OtherNonOperatingIncomeExpenses | -2.00K | -914.00K | 7.00K | -4.00K |
| SpecialIncomeCharges | -25.17M | 0.00 | ||
| RestructuringAndMergernAcquisition | 25.17M | 0.00 | ||
| GainOnSaleOfSecurity | 16.17M | -7.65M | ||
| NetNonOperatingInterestIncomeExpense | 1.43M | 2.47M | 1.26M | 208.00K |
| InterestExpenseNonOperating | 0.00 | 1.00K | 2.00K | 2.00K |
| InterestIncomeNonOperating | 1.43M | 2.47M | 1.27M | 210.00K |
| OperatingIncome | -15.78M | -55.16M | -67.42M | -60.77M |
| OperatingExpense | 15.79M | 58.53M | 68.60M | 62.52M |
| ResearchAndDevelopment | 9.15M | 43.97M | 52.04M | 47.13M |
| SellingGeneralAndAdministration | 6.63M | 14.56M | 16.55M | 15.39M |
| GeneralAndAdministrativeExpense | 6.63M | 14.56M | 16.55M | 15.39M |
| OtherGandA | 6.63M | 14.56M | 16.55M | 15.39M |
| TotalRevenue | 8.00K | 3.37M | 1.18M | 1.75M |
| OperatingRevenue | 8.00K | 3.37M | 1.18M | 1.75M |
| Line Item | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| TreasurySharesNumber | 279.79K | 279.79K | 279.79K | |
| OrdinarySharesNumber | 11.70M | 9.19M | 4.45M | 4.65M |
| ShareIssued | 11.98M | 9.47M | 4.73M | 4.65M |
| TotalDebt | 0.00 | 17.27M | 20.30M | 20.59M |
| TangibleBookValue | 12.75M | 32.77M | 82.61M | 147.27M |
| InvestedCapital | 12.75M | 32.77M | 82.61M | 147.27M |
| WorkingCapital | 12.70M | 19.62M | 67.66M | 123.23M |
| NetTangibleAssets | 12.75M | 32.77M | 82.61M | 147.27M |
| CapitalLeaseObligations | 0.00 | 17.27M | 20.30M | 20.59M |
| CommonStockEquity | 12.75M | 32.77M | 82.61M | 147.27M |
| TotalCapitalization | 12.75M | 32.77M | 82.61M | 147.27M |
| TotalEquityGrossMinorityInterest | 12.75M | 32.77M | 82.61M | 147.27M |
| StockholdersEquity | 12.75M | 32.77M | 82.61M | 147.27M |
| GainsLossesNotAffectingRetainedEarnings | 0.00 | 6.00K | -161.00K | -45.00K |
| OtherEquityAdjustments | 6.00K | -161.00K | -45.00K | |
| TreasuryStock | 2.52M | 2.52M | 2.52M | 0.00 |
| RetainedEarnings | -441.65M | -418.29M | -357.02M | -290.87M |
| AdditionalPaidInCapital | 456.91M | 453.56M | 442.30M | 438.11M |
| CapitalStock | 12.00K | 10.00K | 5.00K | 70.00K |
| CommonStock | 12.00K | 10.00K | 5.00K | 70.00K |
| TotalLiabilitiesNetMinorityInterest | 7.08M | 42.78M | 28.25M | 27.47M |
| TotalNonCurrentLiabilitiesNetMinorityInterest | 0.00 | 12.49M | 16.13M | 17.39M |
| LongTermDebtAndCapitalLeaseObligation | 0.00 | 12.49M | 16.13M | 17.39M |
| LongTermCapitalLeaseObligation | 0.00 | 12.49M | 16.13M | 17.39M |
| CurrentLiabilities | 7.08M | 30.29M | 12.12M | 10.08M |
| OtherCurrentLiabilities | 4.87M | 21.05M | ||
| CurrentDeferredLiabilities | 0.00 | 882.00K | 531.00K | |
| CurrentDeferredRevenue | 0.00 | 882.00K | 531.00K | |
| CurrentDebtAndCapitalLeaseObligation | 4.78M | 4.17M | 3.20M | |
| CurrentCapitalLeaseObligation | 0.00 | 4.78M | 4.17M | 3.20M |
| PayablesAndAccruedExpenses | 2.20M | 4.46M | 7.08M | 6.35M |
| CurrentAccruedExpenses | 2.04M | 3.00M | 5.29M | 4.40M |
| Payables | 164.00K | 1.46M | 1.78M | 1.94M |
| AccountsPayable | 164.00K | 1.46M | 1.78M | 1.94M |
| TotalAssets | 19.83M | 75.55M | 110.86M | 174.74M |
| TotalNonCurrentAssets | 50.00K | 25.64M | 31.08M | 41.43M |
| OtherNonCurrentAssets | 50.00K | 1.11M | 1.10M | 1.10M |
| NonCurrentPrepaidAssets | 0.00 | 6.83M | 8.30M | 9.31M |
| InvestmentsAndAdvances | 0.00 | 8.04M | ||
| InvestmentinFinancialAssets | 0.00 | 8.04M | ||
| AvailableForSaleSecurities | 8.04M | |||
| NetPPE | 0.00 | 17.70M | 21.68M | 22.98M |
| AccumulatedDepreciation | -14.28M | -13.14M | -10.63M | |
| GrossPPE | 0.00 | 31.99M | 34.82M | 33.60M |
| Leases | 9.82M | 9.82M | 9.56M | |
| ConstructionInProgress | 192.00K | 37.00K | 623.00K | |
| OtherProperties | 20.68M | 23.67M | 22.16M | |
| MachineryFurnitureEquipment | 1.29M | 1.29M | 1.26M | |
| Properties | 0.00 | 0.00 | 0.00 | |
| CurrentAssets | 19.78M | 49.91M | 79.78M | 133.31M |
| OtherCurrentAssets | 75.00K | 146.00K | 175.00K | 311.00K |
| AssetsHeldForSaleCurrent | 86.00K | 0.00 | ||
| PrepaidAssets | 755.00K | 2.02M | 1.98M | 4.41M |
| CashCashEquivalentsAndShortTermInvestments | 18.86M | 47.75M | 77.63M | 128.59M |
| OtherShortTermInvestments | 0.00 | 23.79M | 61.77M | 112.15M |
| CashAndCashEquivalents | 18.86M | 23.96M | 15.86M | 16.44M |
| Line Item | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|
| FreeCashFlow | -31.67M | -51.83M | -57.62M | -52.88M |
| RepurchaseOfCapitalStock | 0.00 | -2.52M | 0.00 | |
| RepaymentOfDebt | -4.00K | -13.00K | -13.00K | -8.00K |
| IssuanceOfCapitalStock | 22.00K | 20.83M | 293.00K | 89.09M |
| CapitalExpenditure | -14.00K | -214.00K | -728.00K | -679.00K |
| InterestPaidSupplementalData | 0.00 | 1.00K | 2.00K | 2.00K |
| IncomeTaxPaidSupplementalData | 5.00K | 14.00K | 0.00 | |
| EndCashPosition | 18.91M | 25.06M | 16.96M | 17.54M |
| BeginningCashPosition | 25.06M | 16.96M | 17.54M | 33.60M |
| ChangesInCash | -6.15M | 8.10M | -577.00K | -16.07M |
| FinancingCashFlow | 172.00K | 20.94M | -2.04M | 89.38M |
| CashFlowFromContinuingFinancingActivities | 172.00K | 20.94M | -2.04M | 89.38M |
| NetOtherFinancingCharges | -73.00K | |||
| ProceedsFromStockOptionExercised | 154.00K | 125.00K | 198.00K | 374.00K |
| NetCommonStockIssuance | 22.00K | 20.83M | -2.23M | 89.09M |
| CommonStockPayments | 0.00 | -2.52M | 0.00 | |
| CommonStockIssuance | 22.00K | 20.83M | 293.00K | 89.09M |
| NetIssuancePaymentsOfDebt | -4.00K | -13.00K | -13.00K | -8.00K |
| NetLongTermDebtIssuance | -4.00K | -13.00K | -13.00K | -8.00K |
| LongTermDebtPayments | -4.00K | -13.00K | -13.00K | -8.00K |
| InvestingCashFlow | 25.34M | 38.77M | 58.35M | -53.25M |
| CashFlowFromContinuingInvestingActivities | 25.34M | 38.77M | 58.35M | -53.25M |
| NetInvestmentPurchaseAndSale | 24.02M | 38.97M | 59.08M | -52.57M |
| SaleOfInvestment | 25.50M | 66.90M | 141.87M | 115.29M |
| PurchaseOfInvestment | -1.48M | -27.93M | -82.79M | -167.87M |
| NetPPEPurchaseAndSale | 1.32M | -198.00K | -728.00K | -679.00K |
| SaleOfPPE | 1.33M | 16.00K | 0.00 | |
| PurchaseOfPPE | -14.00K | -214.00K | -728.00K | -679.00K |
| OperatingCashFlow | -31.66M | -51.61M | -56.89M | -52.20M |
| CashFlowFromContinuingOperatingActivities | -31.66M | -51.61M | -56.89M | -52.20M |
| ChangeInWorkingCapital | -11.72M | -6.17M | 723.00K | 200.00K |
| ChangeInOtherWorkingCapital | -882.00K | 351.00K | 531.00K | |
| ChangeInOtherCurrentLiabilities | -12.42M | -4.09M | -3.90M | -2.83M |
| ChangeInOtherCurrentAssets | 16.00K | -9.00K | -4.00K | 1.00K |
| ChangeInPayablesAndAccruedExpense | -2.26M | -2.65M | 697.00K | 538.00K |
| ChangeInPrepaidAssets | 2.94M | 1.47M | 3.58M | 1.96M |
| OtherNonCashItems | -2.32M | 4.24M | 3.15M | 2.10M |
| StockBasedCompensation | 3.17M | 2.81M | 3.64M | 3.36M |
| AssetImpairmentCharge | 19.80M | 0.00 | ||
| AmortizationOfSecurities | -242.00K | -818.00K | -772.00K | 261.00K |
| DepreciationAmortizationDepletion | 347.00K | 1.96M | 2.52M | 2.44M |
| DepreciationAndAmortization | 347.00K | 1.96M | 2.52M | 2.44M |
| Depreciation | 347.00K | 1.96M | 2.52M | 2.44M |
| OperatingGainsLosses | -17.33M | 7.64M | ||
| GainLossOnInvestmentSecurities | -16.17M | 7.65M | ||
| GainLossOnSaleOfPPE | -1.16M | -11.00K | 0.00 | |
| NetIncomeFromContinuingOperations | -23.36M | -61.27M | -66.15M | -60.56M |
SEC Filings
Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.
Public Trades for SYBX
| Date | User | Asset | Broker | Type | Position Size | Entry Price | Patterns |
|---|