XERS Chart
About

Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. The company offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase 3 clinical trial for the treatment of hypothyroidism. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.

Fundamentals
Scroll to Statements
Sector Healthcare Industry Biotechnology Market Cap 1.11B
Enterprise Value 1.27B Income -15.64M Sales 266.14M
Book/sh -0.01 Cash/sh 0.55 Dividend Yield —
Payout 0.00% Employees 394 IPO —
P/E — Forward P/E 21.18 PEG —
P/S 4.15 P/B -1332.00 P/C —
EV/EBITDA 45.46 EV/Sales 4.79 Quick Ratio 1.25
Current Ratio 1.93 Debt/Eq — LT Debt/Eq —
EPS (ttm) -0.10 EPS next Y 0.31 EPS Growth —
Revenue Growth 37.10% Earnings 2026-03-02 ROA 2.88%
ROE — ROIC — Gross Margin 84.56%
Oper. Margin 9.05% Profit Margin -5.88% Shs Outstand 165.92M
Shs Float 157.32M Short Float 10.64% Short Ratio 7.50
Short Interest — 52W High 10.08 52W Low 3.58
Beta 0.93 Avg Volume 2.00M Volume 1.16M
Target Price $11.14 Recom None Prev Close $6.68
Price $6.66 Change -0.30%
Valuation Models

Price estimates from analyst targets and simple models.

1. Analyst consensus
$11.14
Mean price target
2. Current target
$6.66
Latest analyst target
3. DCF / Fair value
$3.10
Simplified: (Free Cash Flow ÷ Shares) × 18 (P/FCF multiple). Not a …
Ratings
Current target
$6.66
Low
$8.00
High
$18.00
Mean
$11.14

Latest analyst rating changes

Date Action Analyst Rating Change Price Target
2026-01-09 reit HC Wainwright & Co. Buy → Buy $10
2025-12-09 init Barclays — → Overweight $9
2025-11-07 main Oppenheimer Outperform → Outperform $18
2025-11-07 main HC Wainwright & Co. Buy → Buy $10
2025-11-07 main Piper Sandler Neutral → Neutral $8
2025-10-29 main Oppenheimer Outperform → Outperform $18
2025-09-17 main HC Wainwright & Co. Buy → Buy $10
2025-08-19 main Leerink Partners Outperform → Outperform $9
2025-08-08 main Craig-Hallum Buy → Buy $11
2025-08-08 main Oppenheimer Outperform → Outperform $8
2025-06-05 main Leerink Partners Outperform → Outperform $7
2025-05-09 main Oppenheimer Outperform → Outperform $7
2025-03-07 reit Piper Sandler Neutral → Neutral $4
2025-03-07 main Leerink Partners Outperform → Outperform $6
2025-03-07 main Craig-Hallum Buy → Buy $7
2025-03-07 reit HC Wainwright & Co. Buy → Buy $8
2025-01-29 reit Jefferies Buy → Buy $6
2024-11-11 main HC Wainwright & Co. Buy → Buy $7
2024-11-11 down Piper Sandler Overweight → Neutral $3
2024-08-15 reit HC Wainwright & Co. Buy → Buy $6
Insider Transactions
Date Shares Value Url Text Insider Position Transaction Start Date Ownership
0 16667 124147 — Sale at price 7.45 per share. HECHT BETH P Officer — 2026-02-02 00:00:00 D
1 121293 — — Stock Award(Grant) at price 0.00 per share. HECHT BETH P Officer — 2026-01-30 00:00:00 D
2 478436 — — Stock Award(Grant) at price 0.00 per share. SHANNON JOHN PATRICK JR Chief Executive Officer — 2026-01-30 00:00:00 D
3 154986 — — Stock Award(Grant) at price 0.00 per share. PIEPER STEVEN Chief Financial Officer — 2026-01-30 00:00:00 D
4 168463 — — Stock Award(Grant) at price 0.00 per share. MCCULLOCH KEVIN President — 2026-01-30 00:00:00 D
5 121293 — — Stock Award(Grant) at price 0.00 per share. NGUYEN ANH TU Officer — 2026-01-30 00:00:00 D
6 15000 120000 — Sale at price 8.00 per share. MCCULLOCH KEVIN President — 2026-01-08 00:00:00 D
7 24907 176257 — Sale at price 7.08 per share. SHANNON JOHN PATRICK JR Chief Executive Officer — 2026-01-05 00:00:00 D
8 92301 149998 — Conversion of Exercise of derivative security at price 1.55 - 3.94 per share. SHANNON JOHN PATRICK JR Chief Executive Officer — 2026-01-05 00:00:00 D
9 16667 123776 — Sale at price 7.43 per share. HECHT BETH P Officer — 2026-01-02 00:00:00 D
Financials
Line Item2024-12-312023-12-312022-12-312021-12-31
TaxEffectOfUnusualItems67.76K46.50K-38.83K0.00
TaxRateForCalcs0.040.020.010.00
NormalizedEBITDA-15.70M-26.10M-66.69M-112.96M
TotalUnusualItems1.71M2.36M-2.62M-702.00K
TotalUnusualItemsExcludingGoodwill1.71M2.36M-2.62M-702.00K
NetIncomeFromContinuingOperationNetMinorityInterest-54.84M-62.26M-94.66M-122.72M
ReconciledDepreciation12.62M13.16M12.67M1.88M
ReconciledCostOfRevenue35.05M26.33M20.81M11.99M
EBITDA-13.99M-23.73M-69.31M-113.67M
EBIT-26.62M-36.90M-81.98M-115.55M
NetInterestIncome-25.16M-21.86M-11.52M-6.87M
InterestExpense30.48M26.61M14.10M7.18M
InterestIncome5.32M4.75M2.58M313.00K
NormalizedIncome-56.47M-64.57M-92.08M-122.02M
NetIncomeFromContinuingAndDiscontinuedOperation-54.84M-62.26M-94.66M-122.72M
TotalExpenses236.72M207.92M192.19M164.75M
TotalOperatingIncomeAsReported-33.65M-44.01M-81.94M-115.16M
DilutedAverageShares146.77M137.67M135.63M79.03M
BasicAverageShares146.77M137.67M135.63M79.03M
DilutedEPS-0.37-0.45-0.70-1.55
BasicEPS-0.37-0.45-0.70-1.55
DilutedNIAvailtoComStockholders-54.84M-62.26M-94.66M-122.72M
NetIncomeCommonStockholders-54.84M-62.26M-94.66M-122.72M
NetIncome-54.84M-62.26M-94.66M-122.72M
NetIncomeIncludingNoncontrollingInterests-54.84M-62.26M-94.66M-122.72M
NetIncomeContinuousOperations-54.84M-62.26M-94.66M-122.72M
TaxProvision-2.27M-1.25M-1.42M0.00
PretaxIncome-57.10M-63.50M-96.08M-122.72M
OtherIncomeExpense1.71M2.36M-2.62M-702.00K
SpecialIncomeCharges1.70M2.36M-4.38M0.00
OtherSpecialCharges2.69M2.84M1.22M
RestructuringAndMergernAcquisition-4.39M-5.20M3.16M0.00
GainOnSaleOfSecurity8.00K1.00K1.76M-702.00K
NetNonOperatingInterestIncomeExpense-25.16M-21.86M-11.52M-6.87M
TotalOtherFinanceCost2.69M
InterestExpenseNonOperating30.48M26.61M14.10M7.18M
InterestIncomeNonOperating5.32M4.75M2.58M313.00K
OperatingIncome-33.65M-44.01M-81.94M-115.16M
OperatingExpense199.88M179.28M169.55M151.43M
DepreciationAmortizationDepletionIncomeStatement10.84M10.84M10.84M550.00K
DepreciationAndAmortizationInIncomeStatement10.84M10.84M10.84M550.00K
Amortization10.84M10.84M10.84M550.00K
AmortizationOfIntangiblesIncomeStatement10.84M10.84M10.84M550.00K
ResearchAndDevelopment25.56M22.34M20.97M25.16M
SellingGeneralAndAdministration163.48M146.09M137.75M125.72M
GrossProfit166.24M135.27M87.61M36.27M
CostOfRevenue36.83M28.64M22.63M13.32M
TotalRevenue203.07M163.91M110.25M49.59M
OperatingRevenue203.07M163.91M110.25M49.59M
Line Item2023-12-31
TreasurySharesNumber0.00
OrdinarySharesNumber149.43M138.13M136.27M124.87M
ShareIssued149.43M138.13M136.27M124.87M
NetDebt160.49M123.48M65.11M20.80M
TotalDebt271.45M229.19M198.06M88.07M
TangibleBookValue-151.40M-139.41M-98.28M-59.08M
InvestedCapital202.49M184.15M232.26M183.30M
WorkingCapital67.22M61.07M113.20M63.56M
NetTangibleAssets-151.40M-139.41M-98.28M-59.08M
CapitalLeaseObligations39.34M38.26M10.98M0.00
CommonStockEquity-29.61M-6.78M45.19M95.23M
TotalCapitalization187.39M184.15M232.26M183.30M
TotalEquityGrossMinorityInterest-29.61M-6.78M45.19M95.23M
StockholdersEquity-29.61M-6.78M45.19M95.23M
GainsLossesNotAffectingRetainedEarnings-25.00K-25.00K-23.00K-31.00K
OtherEquityAdjustments-25.00K-25.00K-23.00K-31.00K
RetainedEarnings-671.86M-617.02M-554.77M-460.11M
AdditionalPaidInCapital642.26M610.25M599.97M555.36M
CapitalStock15.00K14.00K14.00K13.00K
CommonStock15.00K14.00K14.00K13.00K
PreferredStock0.000.000.000.00
TotalLiabilitiesNetMinorityInterest352.68M329.38M299.33M209.13M
TotalNonCurrentLiabilitiesNetMinorityInterest252.23M234.19M225.71M130.09M
OtherNonCurrentLiabilities1.97M6.23M25.72M30.20M
NonCurrentDeferredLiabilities0.002.27M3.52M11.82M
NonCurrentDeferredTaxesLiabilities0.002.27M3.52M4.94M
LongTermDebtAndCapitalLeaseObligation250.26M225.70M196.48M88.07M
LongTermCapitalLeaseObligation33.26M34.76M9.40M0.00
LongTermDebt217.01M190.93M187.07M88.07M
CurrentLiabilities100.44M95.19M73.62M79.04M
OtherCurrentLiabilities1.09M20.28M2.66M1.99M
CurrentDebtAndCapitalLeaseObligation21.18M3.50M1.58M
CurrentCapitalLeaseObligation6.08M3.50M1.58M0.00
CurrentDebt15.10M
OtherCurrentBorrowings15.10M
PensionandOtherPostRetirementBenefitPlansCurrent19.58M16.96M13.40M19.64M
CurrentProvisions19.08M14.20M11.17M4.00M
PayablesAndAccruedExpenses39.51M40.27M44.81M53.41M
CurrentAccruedExpenses37.22M28.70M40.20M44.49M
InterestPayable2.12M1.37M4.66M1.41M
Payables2.29M11.56M4.61M8.92M
AccountsPayable2.29M11.56M4.61M8.92M
TotalAssets323.06M322.60M344.52M304.36M
TotalNonCurrentAssets155.40M166.34M157.70M161.76M
OtherNonCurrentAssets5.41M4.54M4.73M829.00K
GoodwillAndOtherIntangibleAssets121.78M132.62M143.47M154.31M
OtherIntangibleAssets98.92M109.76M120.61M131.45M
Goodwill22.86M22.86M22.86M22.86M
NetPPE28.21M29.18M9.51M6.63M
AccumulatedDepreciation-7.26M-6.04M-5.53M-4.13M
GrossPPE35.47M35.21M15.04M10.76M
Leases6.06M5.98M5.07M5.03M
OtherProperties4.73M4.15M3.84M3.74M
MachineryFurnitureEquipment2.04M1.87M2.14M2.00M
BuildingsAndImprovements22.65M23.20M3.99M0.00
Properties0.000.000.000.00
CurrentAssets167.66M156.26M186.82M142.60M
OtherCurrentAssets7.45M5.78M9.29M4.59M
PrepaidAssets4.59M
Inventory48.17M38.84M24.73M18.12M
FinishedGoods5.45M10.47M5.96M5.50M
WorkInProcess10.99M10.96M11.37M7.44M
RawMaterials31.73M17.40M7.41M5.18M
Receivables40.41M39.20M30.83M17.46M
AccountsReceivable40.41M39.20M30.83M17.46M
CashCashEquivalentsAndShortTermInvestments71.62M72.45M121.97M102.43M
OtherShortTermInvestments0.005.00M0.0035.16M
CashAndCashEquivalents71.62M67.45M121.97M67.27M
Line Item2024-12-312023-12-312022-12-312021-12-31
FreeCashFlow-37.85M-49.29M-103.42M-96.62M
RepurchaseOfCapitalStock-3.73M-1.01M-468.00K-534.00K
RepaymentOfDebt-11.83M0.00-44.23M0.00
IssuanceOfDebt50.00M0.00146.21M0.00
IssuanceOfCapitalStock0.000.0030.00M27.00M
CapitalExpenditure-868.00K-2.26M-524.00K-1.08M
InterestPaidSupplementalData26.95M27.69M10.86M7.29M
EndCashPosition75.74M71.67M126.31M67.27M
BeginningCashPosition71.67M126.31M67.27M37.60M
EffectOfExchangeRateChanges0.000.00-3.00K
ChangesInCash4.07M-54.64M59.04M29.68M
FinancingCashFlow36.17M-1.61M127.47M27.25M
CashFlowFromContinuingFinancingActivities36.17M-1.61M127.47M27.25M
NetOtherFinancingCharges-1.19M-4.88M-54.00K
ProceedsFromStockOptionExercised1.73M581.00K836.00K835.00K
NetCommonStockIssuance-3.73M-1.01M29.53M26.47M
CommonStockPayments-3.73M-1.01M-468.00K-534.00K
CommonStockIssuance0.000.0030.00M27.00M
NetIssuancePaymentsOfDebt38.17M0.00101.98M0.00
NetLongTermDebtIssuance38.17M0.00101.98M0.00
LongTermDebtPayments-11.83M0.00-44.23M0.00
LongTermDebtIssuance50.00M0.00146.21M0.00
InvestingCashFlow4.88M-6.00M34.46M97.96M
CashFlowFromContinuingInvestingActivities4.88M-6.00M34.46M97.96M
NetInvestmentPurchaseAndSale5.75M-3.74M34.98M60.58M
SaleOfInvestment40.24M40.00M34.98M103.60M
PurchaseOfInvestment-34.48M-43.74M0.00-43.02M
NetBusinessPurchaseAndSale0.000.0038.47M
SaleOfBusiness0.000.0038.47M
CapitalExpenditureReported-868.00K-2.26M-524.00K-1.08M
OperatingCashFlow-36.98M-47.02M-102.89M-95.53M
CashFlowFromContinuingOperatingActivities-36.98M-47.02M-102.89M-95.53M
ChangeInWorkingCapital-8.82M-6.29M-35.15M11.85M
ChangeInOtherWorkingCapital3.81M6.42M9.68M-77.00K
ChangeInOtherCurrentLiabilities1.08M818.00K-6.18M0.00
ChangeInPayablesAndAccruedExpense-2.04M6.43M-13.93M22.30M
ChangeInAccruedExpense7.57M-524.00K-9.61M16.77M
ChangeInPayable-9.61M6.96M-4.32M5.53M
ChangeInAccountPayable-9.61M6.96M-4.32M5.53M
ChangeInPrepaidAssets-1.67M3.21M-3.89M3.29M
ChangeInInventory-8.78M-14.80M-7.46M-7.42M
ChangeInReceivables-1.22M-8.37M-13.37M-6.24M
ChangesInAccountReceivables-1.22M-8.37M-13.37M-6.24M
OtherNonCashItems-1.38M-3.00M3.63M961.00K
StockBasedCompensation18.36M10.72M12.16M11.38M
AmortizationOfSecurities-747.00K-1.26M184.00K413.00K
DeferredTax-2.27M-1.25M-1.42M0.00
DeferredIncomeTax-2.27M-1.25M-1.42M0.00
DepreciationAmortizationDepletion12.62M13.16M12.67M1.88M
DepreciationAndAmortization12.62M13.16M12.67M1.88M
AmortizationCashFlow10.84M10.84M10.84M550.00K
AmortizationOfIntangibles10.84M10.84M10.84M550.00K
Depreciation1.78M2.32M1.82M1.33M
OperatingGainsLosses83.00K3.16M-301.00K702.00K
GainLossOnInvestmentSecurities-8.00K-1.00K-1.76M702.00K
GainLossOnSaleOfPPE91.00K321.00K236.00K0.00
NetIncomeFromContinuingOperations-54.84M-62.26M-94.66M-122.72M
SEC Filings

Recent 10-K, 10-Q, 8-K, and Form 4 (insider) filings.

Public Trades for XERS
Date User Asset Broker Type Position Size Entry Price Patterns